CAS 22059-60-5

Disopyramide phosphate

Description:

Disopyramide phosphate is a pharmaceutical compound primarily used as an antiarrhythmic agent to treat certain types of irregular heartbeats. It is a member of the class IA antiarrhythmics, which work by blocking sodium channels in cardiac tissues, thereby stabilizing the cardiac membrane and reducing excitability. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in clinical settings. Disopyramide phosphate has a relatively long half-life, allowing for less frequent dosing compared to some other antiarrhythmic medications. Its pharmacological effects include negative inotropic and chronotropic actions, which can lead to decreased heart rate and contractility. However, it may also cause side effects such as dry mouth, urinary retention, and blurred vision due to its anticholinergic properties. As with any medication, its use should be carefully monitored, particularly in patients with pre-existing conditions or those taking other medications that may interact with its effects.

Formula: C₂₁H₂₉N₃O·H₃O₄P

InChI: InChI=1S/C21H29N3O.H3O4P/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19;1-5(2,3)4/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25);(H3,1,2,3,4)

InChI key: InChIKey=CGDDQFMPGMYYQP-UHFFFAOYSA-N

SMILES: P(=O)(O)(O)O.C(CCN(C(C)C)C(C)C)(C(N)=O)(C1=CC=CC=C1)C2=CC=CC=N2

Synonyms:

• (+-)-alpha-(2-(Diisopropylamino)ethyl)-alpha-phenyl-2-pyridineacetamide phosphate (1:1)
• 2-(1-(Ammoniocarbonyl)-3-(diisopropylammonio)-1-phenylpropyl)pyridinium phosphate
• 2-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-, (+-)-, phosphate (1:1)
• 2-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-, phosphate (9CI)
• 2-Pyridineacetamide, alpha-(2-(diisopropylamino)ethyl)-alpha-phenyl-, phosphate
• 2-Pyridineacetamide, α-[2-(diisopropylamino)ethyl]-α-phenyl-, phosphate (1:1)
• 2-Pyridineacetamide, α-[2-[bis(1-methylethyl)amino]ethyl]-α-phenyl-, phosphate (1:1)
• 4-(Dipropan-2-Ylamino)-2-Phenyl-2-(Pyridin-2-Yl)Butanamide
• 4-(Dipropan-2-Ylamino)-2-Phenyl-2-(Pyridin-2-Yl)Butanamide Phosphate (1:1)
• 4-Diisopropylamino-2-phenyl-2-(2-pyridyl)butyramide phosphate
• Dirythmin SA
• Diso-Duriles
• Disopyramide dihydrogen phosphate
• Disopyramide phosphate [USAN:BAN:JAN]
• Norpace
• Norpace CR
• Rythmodan
• Rythmodan P
• Rythmodul
• SC 7031 phosphate
• Sc 13957
• Unii-N6Bom1935W
• alpha-(2-Diisopropylaminoethyl)-alpha-phenyl-2-pyridineacetamide phosphate
• Disopyramide phosphate

DISOPYRAMIDE PHOSPHATE CRS

CAS: 22059-60-5

DISOPYRAMIDE PHOSPHATE CRS

Formula: C₂₁H₃₂N₃O₅P

Color and Shape: White. Whitish. Powder.

Molecular weight: 437.4696

Ref: 41-D2922000

Disopyramide Phosphate

CAS: 22059-60-5

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₂₁H₂₉N₃O·H₃O₄P

Color and Shape: Off-White Powder

Molecular weight: 437.20796

Ref: 45-1222501

Disopyramide phosphate salt

CAS: 22059-60-5

Formula: C₂₁H₂₉N₃O·H₃PO₄

Molecular weight: 437.47

Ref: 7W-GK3500

4-(Diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide phosphate

CAS: 22059-60-5

4-(Diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide phosphate

Purity: 98%

Molecular weight: 437.48g/mol

Ref: 54-OR1061760

Disopyramide phosphate

CAS: 22059-60-5

Disopyramide: Class 1a anti-arrhythmic, treats Ventricular Tachycardia, reduces heart muscle contractility.

Formula: C₂₁H₃₂N₃O₅P

Color and Shape: Solid

Molecular weight: 437.47

Ref: TM-T21424

Disopyramide Phosphate

Controlled Product

CAS: 22059-60-5

Formula: C₂₁H₂₉N₃O·H₃O₄P

Color and Shape: Neat

Molecular weight: 437.47

Ref: TR-D493455

Disopyramide Phosphate

CAS: 22059-60-5

Formula: C₂₁H₂₉N₃OH₃PO₄

Molecular weight: 339.48 : 97.99

Ref: ST-EA-CP-D169005

Disopyramid phosphate

Controlled Product

CAS: 22059-60-5

Disopyramide is a pharmacological agent that belongs to the class of agents known as antiarrhythmics. It is used in the treatment of ventricular arrhythmias, and has been shown to be effective in patients with congestive heart failure. Disopyramide has a high affinity for the ryanodine receptor and blocks intracellular calcium release from the sarcoplasmic reticulum by binding to this site. It also has an effect on atrial contractility, leading to increased heart rate, and a minimal toxicity profile. The drug does not cause hypoglycemia or structural cardiac disease in animals.

Formula: C₂₁H₃₂N₃O₅P

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 437.47 g/mol

Ref: 3D-XAA05960