CAS 2206825-87-6

Apixaban Open Chain Acid Impurity

CAS: 2206825-87-6

Formula: C₂₅H₂₇N₅O₅

Color and Shape: Pale Yellow Solid

Molecular weight: 477.52

Ref: 4Z-A-10221

5-((4-(3-Carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydro-1H-pyrazolo[3,4-c]pyridin-6(7H)-yl)phenyl)amino)pentanoic acid

CAS: 2206825-87-6

5-((4-(3-Carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydro-1H-pyrazolo[3,4-c]pyridin-6(7H)-yl)phenyl)amino)pentanoic acid

Purity: 97%

Molecular weight: 477.52g/mol

Ref: 54-OR1074245

5-[[4-[3-(Aminocarbonyl)-1,4,5,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6H-pyrazolo[3,4-c]pyridin-6-yl]phenyl]amino]pentanoic Acid

CAS: 2206825-87-6

Color and Shape: Neat

Ref: 86-MM3754.04

Apixaban Amino Acid Impurity

CAS: 2206825-87-6

Formula: C₂₅H₂₇N₅O₅

Molecular weight: 477.52

Ref: ST-EA-CP-A3009

5-[[4-[3-(Aminocarbonyl)-1,4,5,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6H-pyrazolo[3,4-c]pyridin-6-yl]phenyl]amino]pentanoic Acid

CAS: 2206825-87-6

Applications Apixaban Open chain Acid Is an open ring impurity of Apixaban (A726700). Apixaben is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.
References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);

Formula: C₂₅H₂₇N₅O₅

Color and Shape: Light Yellow

Molecular weight: 477.51

Ref: TR-A875620