CAS 2208-12-0
:6-Dehydroestrone
Description:
6-Dehydroestrone is a steroid hormone and a derivative of estrone, classified under the category of estrogens. It is characterized by its structural modifications that include the absence of a hydrogen atom at the 6-position of the estrone molecule, which contributes to its unique biological activity. This compound is typically found in trace amounts in the human body and is involved in various physiological processes, including the regulation of the menstrual cycle and reproductive functions. Its chemical formula reflects its steroidal nature, and it exhibits properties typical of estrogens, such as binding to estrogen receptors and influencing gene expression. 6-Dehydroestrone can be synthesized in the laboratory and is of interest in research related to hormonal therapies and endocrine functions. As with many steroid hormones, it is important to handle this compound with care due to its potential biological effects and the need for precise dosage in therapeutic applications.
Formula:C18H20O2
InChI:InChI=1S/C18H20O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h2-5,10,14-16,19H,6-9H2,1H3/t14-,15-,16+,18+/m1/s1
InChI key:InChIKey=WTRRIQCGCGCMQA-CBZIJGRNSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@](C=4C(C=C3)=CC(O)=CC4)(CC1)[H])[H])(CCC2=O)[H]
Synonyms:- 1,3,5(10),6-Estratetraen-3beta-ol-17-one
- 3-Heto
- 3-Hydroxyestra-1,3,5(10),6-tetraen-17-one
- 6,7-Dehydroestrone
- 6,7-Didehydroestrone
- 6-Dehydroestrone
- Dehydro-estrone
- Estra-1,3,5(10),6-tetraen-17-one, 3-hydroxy-
- Estra-1,3,5(10),6-tetraen-17-one, 3-hydroxy- (8CI)(9CI)
- Nsc 48999
- delta6,7-Estrone
- delta6-Estrone
- Δ<sup>6,7</sup>-Estrone
- Δ<sup>6</sup>-Estrone
- Δ6-Estrone
- See more synonyms
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Found 2 products.
6-Dehydroestrone
CAS:Controlled Product<p>Dehydroepiandrosterone (DHEA) is a steroid hormone that is produced in the adrenal glands and gonads. The conversion of DHEA to estrone, androstenedione, and testosterone takes place in the liver. The enzymes involved in this conversion are CYP17A1, 17B1, and 17B2, which convert DHEA to estrone and testosterone; CYP17A1 also converts DHEA to androstenedione. Estrogens bind to estrogen receptors on cells throughout the body, influencing gene expression and protein synthesis. Estradiol binds with high affinity to the estrogen receptor alpha (ERα), while other estrogens such as estrone bind to ERβ with lower affinity. 6-Dehydroestrone is an intermediate metabolite of estradiol that can be detected in urine samples using a tritiated compound assay.</p>Formula:C18H20O2Purity:Min. 95%Molecular weight:268.35 g/mol

