CAS 2208-41-5

6-Hydroxymelatonin

Description:

6-Hydroxymelatonin is a derivative of melatonin, a hormone primarily involved in regulating sleep-wake cycles. This compound is characterized by the presence of a hydroxyl group at the 6-position of the indole ring, which distinguishes it from melatonin. It is known for its potential antioxidant properties, which may contribute to its biological activities. The molecular formula of 6-hydroxymelatonin reflects its structure, comprising carbon, hydrogen, nitrogen, and oxygen atoms. This compound is soluble in polar solvents, which facilitates its interaction with biological systems. Research suggests that 6-hydroxymelatonin may play a role in various physiological processes, including modulation of circadian rhythms and neuroprotection. Its pharmacological profile is still under investigation, but it is considered to have potential therapeutic applications in sleep disorders and other conditions influenced by melatonin levels. As with many compounds, further studies are necessary to fully elucidate its mechanisms of action and potential benefits in clinical settings.

Formula: C₁₃H₁₆N₂O₃

InChI: InChI=1/C13H16N2O3/c1-8(16)14-4-3-9-7-15-11-6-12(17)13(18-2)5-10(9)11/h5-7,15,17H,3-4H2,1-2H3,(H,14,16)

InChI key: InChIKey=OMYMRCXOJJZYKE-UHFFFAOYSA-N

SMILES: C(CNC(C)=O)C=1C=2C(=CC(O)=C(OC)C2)NC1

Synonyms:

• 6-Hydroxy-N-acetyl-5-methoxytryptamine
• Acetamide, N-(2-(6-hydroxy-5-methoxy-1H-indol-3-yl)ethyl)- (9CI)
• Acetamide, N-(2-(6-hydroxy-5-methoxyindol-3-yl)ethyl)-
• Acetamide, N-[2-(6-hydroxy-5-methoxy-1H-indol-3-yl)ethyl]-
• Brn 0483231
• Ccris 3473
• N-(2(6-Hydroxy-5-methoxy-1H-indol-3-yl)ethyl)acetamide
• 5-22-12-00353 (Beilstein Handbook Reference)
• 6-Hydroxymelatonin
• 3-[N-ACETYLAMINOETHYL]-6-HYDROXY-5-METHOXYINDOLE
• N-[2-(5-Methoxy-6-hydroxy-1H-indole-3-yl)ethyl]acetamide
• Melatonin 6-Hydroxy Impurity
• Melatonin Impurity 3 (6-Hydroxy Melatonin)
• N-Acetyl-5-methoxy-6-hydroxy-1H-indole-3-ethanamine
• N-ACETYL-6-HYDROXY-5-METHOXYTRYPTAMINE
• 6-Hydroxymelatonine
• n-(2-(6-hydroxy-5-methoxyindol-3-yl)ethyl)-acetamid
• MELATONIN, 6-HYDROXY
• 3-[2-(Acetylamino)ethyl]-5-methoxy-1H-indole-6-ol
• Sutan (Butylate)

6-Hydroxymelatonin

CAS: 2208-41-5

Formula: C₁₃H₁₆N₂O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 248.2777

Ref: IN-DA007PTY

6-Hydroxy Melatonin

CAS: 2208-41-5

Formula: C₁₃H₁₆N₂O₃

Color and Shape: White To Off-White Solid

Molecular weight: 248.28

Ref: 4Z-M-765

6-Hydroxymelatonin

CAS: 2208-41-5

Formula: C₁₃H₁₆N₂O₃

Molecular weight: 248.28

Ref: 7W-GK5395

6-Hydroxymelatonin

CAS: 2208-41-5

6-Hydroxymelatonin

Purity: ≥95%

Molecular weight: 248.28g/mol

Ref: 54-BUP22084

6-Hydroxymelatonin

CAS: 2208-41-5

6-Hydroxymelatonin is a chemoattractant protein that is involved in the regulation of iron homeostasis. It has been shown to have antioxidative properties and can be used for the treatment of cancer. 6-Hydroxymelatonin also has glucuronide conjugate, which can be detected using LC-MS/MS methods. In vivo studies on humans have shown that 6-hydroxymelatonin stimulates human macrophages and skin cells. Melatonin treatment has been shown to decrease the levels of 6-hydroxymelatonin in humans, which may lead to its anti-inflammatory effects.

Formula: C₁₃H₁₆N₂O₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 248.28 g/mol

Ref: 3D-FH24036

6-Hydroxy Melatonin

CAS: 2208-41-5

Applications A metabolite of Melatonin (M215000).
References Huether, G., et al.: Life Sci., 51, 945 (1992), Holmes, M., et al.: J. Clin. Oncol., 18, 3668 (2000), Roth, G., et al.: J. Clin. Endocrinol. Metab., 86, 3292 (2001),

Formula: C₁₃H₁₆N₂O₃

Color and Shape: White To Beige

Molecular weight: 248.28

Ref: TR-H944625

6-Hydroxy Melatonin

CAS: 2208-41-5

Formula: C₁₃H₁₆N₂O₃

Molecular weight: 248.28

Ref: ST-EA-CP-M166011

6-Hydroxymelatonin

CAS: 2208-41-5

6-Hydroxymelatonin is the main active endogenous metabolite of Melatonin via CYP1A2, an agonist of MT2 receptor antioxidant and neuroprotective.

Formula: C₁₃H₁₆N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 248.28

Ref: TM-T13520