CAS 221054-79-1

(+)-Equol

Description:

(+)-Equol is a chiral compound classified as a phytoestrogen, primarily derived from the metabolism of soy isoflavones, particularly daidzein, by gut microbiota. It exhibits a molecular structure characterized by a phenolic ring and a hydroxyl group, contributing to its estrogenic activity. This compound is known for its ability to bind to estrogen receptors, potentially influencing various physiological processes, including hormone regulation and bone health. (+)-Equol is recognized for its antioxidant properties and may play a role in reducing the risk of certain diseases, such as hormone-related cancers and cardiovascular conditions. Its stereochemistry is significant, as the (+) enantiomer is the biologically active form, while the (-) form is less active. The compound is soluble in organic solvents and has limited solubility in water, which affects its bioavailability. Research continues to explore its therapeutic potential and the implications of equol production in individuals, as not everyone possesses the gut bacteria necessary for its synthesis from dietary sources.

Formula: C₁₅H₁₄O₃

InChI: InChI=1S/C15H14O3/c16-13-4-1-10(2-5-13)12-7-11-3-6-14(17)8-15(11)18-9-12/h1-6,8,12,16-17H,7,9H2/t12-/m0/s1

InChI key: InChIKey=ADFCQWZHKCXPAJ-LBPRGKRZSA-N

SMILES: OC=1C=C2C(C[C@@H](CO2)C3=CC=C(O)C=C3)=CC1

Synonyms:

• (3R)-3,4-Dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol
• (+)-Equol
• 2H-1-Benzopyran-7-ol, 3,4-dihydro-3-(4-hydroxyphenyl)-, (3R)-
• Isoequol
• (R)-Equol

(R)-Equol

CAS: 221054-79-1

(R)-Equol ((+)-Equol) is an ERα and ERβ agonist with Kis of 27.4 and 15.4 nM, respectively.

Formula: C₁₅H₁₄O₃

Purity: 99.59%

Color and Shape: Solid

Molecular weight: 242.27

Ref: TM-T13443

(+)-Equol

CAS: 221054-79-1

Formula: C₁₅H₁₄O₃

Purity: 99%

Color and Shape: Solid

Molecular weight: 242.2699

Ref: IN-DA00BE9U

(R)-Equol

CAS: 221054-79-1

(R)-Equol

Purity: ≥98%

Molecular weight: 242.27g/mol

Ref: 54-BUP10301

(R)-Equol

CAS: 221054-79-1

Formula: C₁₅H₁₄O₃

Molecular weight: 242.27

Ref: 4Z-E-234005

(R)-3-(4-Hydroxyphenyl)Chroman-7-Ol

CAS: 221054-79-1

(R)-3-(4-Hydroxyphenyl)Chroman-7-Ol

Purity: 99%

Molecular weight: 242.27g/mol

Ref: 54-OR1027308

(R)-3-(4-HYDROXYPHENYL)CHROMAN-7-OL

CAS: 221054-79-1

Purity: 99%

Molecular weight: 242.2740021

Ref: 10-F852178

(R)-Equol

Controlled Product

CAS: 221054-79-1

Formula: C₁₅H₁₄O₃

Color and Shape: Neat

Molecular weight: 242.27

Ref: TR-E593038

R-Equol

CAS: 221054-79-1

R-Equol is a chiral compound classified as an isoflavandiol, which is a type of non-steroidal estrogen. It is derived from the metabolic conversion of daidzein, an isoflavone predominantly found in soy products, by intestinal microbiota in some individuals. The presence of equol-producing bacteria is necessary for this biotransformation process.

Purity: Min. 95%

Ref: 3D-FE139179