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CAS 221093-33-0

:

Estra-1,3,5(10)-triene-1,4,16,16,17-d5-2,3,17-triol,(17b)-

Description:
Estra-1,3,5(10)-triene-1,4,16,16,17-d5-2,3,17-triol, also known by its CAS number 221093-33-0, is a synthetic derivative of estradiol, a naturally occurring estrogen. This compound is characterized by its specific deuterated structure, which includes five deuterium atoms replacing hydrogen atoms in the steroid framework. The presence of these deuterium atoms can influence the compound's metabolic stability and pharmacokinetics. The molecule features a triene system, indicating the presence of three double bonds within its steroid backbone, which is typical of steroid hormones. Additionally, the hydroxyl groups at positions 2, 3, and 17 contribute to its biological activity, particularly in estrogen receptor binding. This compound is primarily used in research settings, particularly in studies related to hormone action, metabolism, and the development of therapeutic agents targeting estrogen-related conditions. Its unique isotopic labeling allows for advanced analytical techniques, such as mass spectrometry, to trace its behavior in biological systems.
Formula:C18H19D5O3
Synonyms:
  • 2-Hydroxy-17Beta-Estradiol-1,4,16,16,17-D5
  • (17b)-Estra-1,3,5(10)-triene-2,3,17-triol-d5
  • 2-Hydroxy-17b-estradiol-1,4,16,16,17-d5
  • 2-Hydroxyestradiol-1,4,16,16,17-d5
  • Estra-1,3,5(10)-triene-2,3,17b-triol-d5
  • NSC 61711-d5
  • (17)-Estra-1,3,5(10)-triene-2,3,17-triol-d5
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Found 2 products.
  • 2-Hydroxy-17β-estradiol-1,4,16,16,17-d5
    Cluzeau
    + Info

    2-Hydroxy-17β-estradiol-1,4,16,16,17-d5

    CAS:
    Purity:97 atom % D
    Color and Shape:White Solid
    Molecular weight:293.42

    Ref: 3U-D5552

    5mg
    3,360.00€
  • 2-Hydroxy-17b-estradiol-16,16,17-d5
    TRC
    + Info

    2-Hydroxy-17b-estradiol-16,16,17-d5

    Controlled Product
    CAS:
    <p>Applications A labelled metabolite of Estradiol.<br>References Bucala, R., et al.: J. Clin. Endocrinol. Metab., 60, 841 (1985), Telang, N., et al.: Anticancer Res., et al.: 11, 1021 (1991), Seeger, H., et al.: Med. Sci. Res., 26, 481 (1998), Bolton, J., et al.: Chem. Res. Toxicol., 13, 135 (2000),<br></p>
    Formula:C18D5H19O3
    Color and Shape:Neat
    Molecular weight:293.41

    Ref: TR-H941892

    5mg
    2,797.00€
    500µg
    412.00€