CAS 221093-45-4

Estra-1,3,5(10)-triene-2,4,16,16,17-d5-3,17-diol,(17b)-

Description:

Estra-1,3,5(10)-triene-2,4,16,16,17-d5-3,17-diol, also known by its CAS number 221093-45-4, is a synthetic steroid compound that belongs to the class of estrogens. This compound is characterized by its unique molecular structure, which includes a triene system and multiple hydroxyl (-OH) groups, contributing to its biological activity. The presence of deuterium atoms (indicated by the "d" in its name) suggests that it is a labeled compound, often used in research to trace metabolic pathways or in pharmacokinetic studies. Estra-1,3,5(10)-triene-2,4,16,16,17-d5-3,17-diol exhibits estrogenic activity, making it relevant in studies related to hormone replacement therapy and reproductive health. Its specific stereochemistry, particularly the (17b) designation, indicates the orientation of substituents around the steroid nucleus, which is crucial for its interaction with estrogen receptors. Overall, this compound serves as an important tool in both clinical and laboratory settings for understanding estrogenic effects and mechanisms.

Formula: C₁₈H₁₉D₅O₂

Estradiol-d5

CAS: 221093-45-4

Formula: C₁₈H₁₉D₅O₂

Molecular weight: 277.42

Ref: 4Z-E-095

17β-Estradiol-2,4,16,16,17-d5

CAS: 221093-45-4

Purity: 98 atom % D

Color and Shape: White Solid

Molecular weight: 277.42

Ref: 3U-D5403

17β-Estradiol-2,4,16,16,17-d5

Controlled Product

CAS: 221093-45-4

Applications 17beta-Estradiol-2,4,16,16,17-d5 (CAS# 221093-45-4) is a useful isotopically labeled research compound.

Formula: C₁₈₂H₅H₁₉O₂

Color and Shape: Neat

Molecular weight: 277.41

Ref: TR-E888006

17β-Estradiol-d5 solution

Controlled Product

CAS: 221093-45-4

17β-Estradiol-d5 is a derivative of estradiol that can be used for the preparation of immobilized estrogen receptors. 17β-Estradiol-d5 has been covalently immobilized to a magnetic bead and has been shown to have high affinity for estrogen receptors. The immobilization process was carried out by using a multiwell immobilization method, followed by activation with benzoate. The resulting product was then separated from the beads by using an alcohol solution. This preparative method allows for the production of large quantities of activated estrogen receptor without any loss in quality or purity.

Formula: C₁₈H₂₄O₂

Purity: Min. 95%

Molecular weight: 277.4 g/mol

Ref: 3D-WIA09345