CAS 221244-14-0: 1-(1,1-Dimethylethyl)-3-(1-naphthalenylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Description: 1-(1,1-Dimethylethyl)-3-(1-naphthalenylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, with the CAS number 221244-14-0, is a chemical compound that belongs to the class of pyrazolopyrimidines. This compound features a pyrazolo[3,4-d]pyrimidine core, which is characterized by a fused bicyclic structure that includes both pyrazole and pyrimidine rings. The presence of a 1-naphthalenylmethyl group and a tert-butyl group (1,1-dimethylethyl) contributes to its unique properties, potentially influencing its solubility, stability, and biological activity. Such compounds are often investigated for their pharmacological potential, including roles in medicinal chemistry as kinase inhibitors or in other therapeutic applications. The molecular structure suggests that it may exhibit interesting interactions with biological targets, making it a subject of interest in drug discovery and development. As with many organic compounds, its physical properties, such as melting point, boiling point, and solubility, would need to be determined experimentally for specific applications.

Formula: C₂₀H₂₁N₅

InChI: InChI=1S/C20H21N5/c1-20(2,3)25-19-17(18(21)22-12-23-19)16(24-25)11-14-9-6-8-13-7-4-5-10-15(13)14/h4-10,12H,11H2,1-3H3,(H2,21,22,23)

InChI key: InChIKey=GDQXJQSQYMMKRA-UHFFFAOYSA-N

SMILES: N=1C=NC2=C(C1N)C(=NN2C(C)(C)C)CC3=CC=CC=4C=CC=CC43

Synonyms:

• 1-(1,1-Dimethylethyl)-3-(1-naphthalenylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
• 1-Nm-Pp 1
• 1-Nm-Pp1
• 1-Nmpp1
• 1-tert-Butyl-3-(naphthalen-1-ylmethyl)pyrazolo[3,4-d]pyrimidin-4-amine
• 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-(1,1-dimethylethyl)-3-(1-naphthalenylmethyl)-
• PP 1 Analog II

PP1 Analog II, 1NM-PP1

CAS: 221244-14-0

• Formula: C₂₀H₂₁N₅
• Purity: 98%
• Color and Shape: Liquid
• Molecular weight: 331.4142

1-NM-PP1

CAS: 221244-14-0

• Purity: 99.19%
• Molecular weight: 331.41g/mol

1-NM-PP1

CAS: 221244-14-0

1-NM-PP1 (PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and …

• Formula: C₂₀H₂₁N₅
• Purity: 98% - 98.93%
• Color and Shape: White Cyrstalline Solid
• Molecular weight: 331.41

4-Amino-1-tert-butyl-3-(1’-naphthylmethyl)pyrazolo[3,4-d]pyrimidine

CAS: 221244-14-0

Applications A highly potent (IC50=4.3 nM) and uniquely specific tyrosine kinase inhibitor of a rationally …

• Formula: C₂₀H₂₁N₅
• Color and Shape: Off White Solid
• Molecular weight: 331.41

1-NM-PP1

CAS: 221244-14-0

1-NM-PP1, also known as 1NM-PP1, is an inhibitor of the Src kinase. Studies have shown …

• Formula: C₂₀H₂₁N₅
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 331.1797