CAS 22128-62-7

Chloromethyl chloroformate

Description:

Chloromethyl chloroformate, with the CAS number 22128-62-7, is an organic compound that belongs to the class of chloroformates. It is characterized by its reactive nature, primarily due to the presence of both chloro and formate functional groups. This compound typically appears as a colorless to pale yellow liquid and has a pungent odor. It is soluble in organic solvents such as dichloromethane and ether but is generally insoluble in water. Chloromethyl chloroformate is known for its use as a reagent in organic synthesis, particularly in the formation of esters and in the introduction of chloromethyl groups into various organic molecules. Due to its reactivity, it can pose hazards, including being corrosive and toxic, necessitating careful handling and storage under controlled conditions. Proper safety measures, including the use of personal protective equipment, are essential when working with this compound to mitigate risks associated with its chemical properties.

Formula: C₂H₂Cl₂O₂

InChI: InChI=1S/C2H2Cl2O2/c3-1-6-2(4)5/h1H2

InChI key: InChIKey=JYWJULGYGOLCGW-UHFFFAOYSA-N

SMILES: O(C(Cl)=O)CCl

Synonyms:

• 1-Chloromethyl chloroformate
• 2-Chloromethyl chloroformate
• Carbonochloridic Acid, Chloromethyl Ester
• Chlormethylchlorocarbonat
• Chlorocarbonate de chlorométhyle
• Chloroformic acid chloromethyl ester
• Chloromethoxycarbonyl chloride
• Chloromethyl carbonochloridate
• Chloromethyl chlorocarbonate
• Formic acid, chloro-, chloromethyl ester
• Chloromethyl chloroformate

Chloromethyl Chloroformate

CAS: 22128-62-7

Formula: C₂H₂Cl₂O₂

Purity: >95.0%(GC)(T)

Color and Shape: Colorless to Light yellow to Light orange clear liquid

Molecular weight: 128.94

Ref: 3B-C1396

Chloromethyl chloroformate, 97%

CAS: 22128-62-7

Chloromethyl chloroformate is used as an intermediate in pharmaceuticals and in manufacture other chemicals. It acts as a reactant in the synthesis of aminocarbonyloxymethyl esters of diclofenac, flufenamic acid and in monomethoxypoly(ethyleneglycol) prodrugs of cyclosporin A. This Thermo Scientifi

Formula: C₂H₂Cl₂O₂

Purity: 97%

Color and Shape: Liquid or viscous liquid, Clear colorless

Molecular weight: 128.94

Ref: 02-L09527

Tenofovir Impurity 72

CAS: 22128-62-7

Formula: C₂H₂Cl₂O₂

Molecular weight: 128.94

Ref: 4Z-T-02117

Chloromethyl chloroformate

CAS: 22128-62-7

Formula: C₂H₂Cl₂O₂

Purity: 95.0%

Color and Shape: Liquid

Molecular weight: 128.94

Ref: 10-F320123

Chloroformic Acid Chloromethyl Ester

Controlled Product

CAS: 22128-62-7

Stability Very Very Moisture sensitive
Applications Chloroformic Acid Chloromethyl Ester is used as a reagent in the synthesis of carbamates and carbonates.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Safadi, M. et al.: Pharm. Res. 10, 1350 (1993); Loren, J.C. et al.: Synlett, 18, 2847 (2005);

Formula: C₂H₂Cl₂O₂

Color and Shape: Colourless Oily

Molecular weight: 128.94

Ref: TR-C366500