CAS 221287-83-8

[(3R,4R,5R,6R)-3,4,5-trihydroxy-6-[2-[(5-nitrothiazol-2-yl)carbamoyl]phenoxy]tetrahydropyran-2-carbonyl]oxysodium

Description:

The chemical substance with the name "[(3R,4R,5R,6R)-3,4,5-trihydroxy-6-[2-[(5-nitrothiazol-2-yl)carbamoyl]phenoxy]tetrahydropyran-2-carbonyl]oxysodium" and CAS number "221287-83-8" is characterized by its complex molecular structure, which includes a tetrahydropyran ring, multiple hydroxyl groups, and a nitrothiazole moiety. This compound is likely to exhibit significant solubility in polar solvents due to the presence of hydroxyl groups, which can form hydrogen bonds. The nitrothiazole group may impart biological activity, potentially making it relevant in pharmaceutical applications. The sodium salt form suggests enhanced solubility and bioavailability, which is often desirable in drug formulation. Additionally, the stereochemistry indicated by the (3R,4R,5R,6R) configuration suggests specific spatial arrangements that could influence the compound's interaction with biological targets. Overall, this substance may possess unique properties that could be explored for therapeutic uses, particularly in areas related to antimicrobial or anticancer activities, although specific biological effects would require further investigation.

Formula: C₁₆H₁₄N₃NaO₁₀S

InChI: InChI=1/C16H15N3O10S.Na/c20-9-10(21)12(14(24)25)29-15(11(9)22)28-7-4-2-1-3-6(7)13(23)18-16-17-5-8(30-16)19(26)27;/h1-5,9-12,15,20-22H,(H,24,25)(H,17,18,23);/q;+1/p-1/t9-,10-,11-,12?,15+;/m1./s1

SMILES: c1ccc(c(c1)C(=Nc1ncc(N(=O)=O)s1)O)OC1C(C(C(C(C(=O)O)O1)O)O)O.[Na]

Synonyms:

• 2-[[(5-Nitro-2-thiazolyl)aMino]carbonyl]phenyl β-D-Glucopyranosiduronic Acid
• 2-[[(5-Nitro-2-thiazolyl)amino]carbonyl]phenyl -D-Glucopyranosiduronic Acid Monosodium Salt
• TIZOXANIDE GLUCURONIDE, SODIUM SALT
• Tizoxanide-d4 Glucuronide

Tizoxanide-d4 Glucuronide Sodium Salt

CAS: 221287-83-8

Formula: C₁₆H₁₀D₄N₃O₁₀S·Na

Color and Shape: Yellow Solid

Molecular weight: 444.38 22.99

Ref: 4Z-T-444

Tizoxanide Glucuronide Sodium Salt

CAS: 221287-83-8

Formula: C₁₆H₁₄N₃O₁₀S·Na

Color and Shape: Yellow Solid

Molecular weight: 440.36 22.99

Ref: 4Z-T-443

Tizoxanide Glucuronide Sodium Salt

CAS: 221287-83-8

Applications A metabolite of Nitazoxanide (N490100).
References Honma, K., et al.: Chem. Pharm. Bull., 24, 394 (1976), Dubreuil, L., et al.: Antimicrob. Agents Chemother., 40, 2266 (1996), Stockis, A., et al.: Int. J. Clin. Pharmacol. Ther., 34, 349 (1996),

Formula: C₁₆H₁₄N₃O₁₀S·Na

Color and Shape: Neat

Molecular weight: 463.35

Ref: TR-T450115

Tizoxanide-d4 Glucuronide Sodium Salt

Controlled Product

CAS: 221287-83-8

Formula: C₁₆D₄H₁₀N₃O₁₀S·Na

Color and Shape: Dark Yellow

Molecular weight: 467.38

Ref: TR-T450118

Tizoxanide O-b-D-glucuronide sodium salt

CAS: 221287-83-8

Tizoxanide O-b-D-glucuronide sodium salt is a synthetic glycosylate of tizoxanide, which is a sulfonamide antibacterial agent. The drug has broad-spectrum activity against Gram-positive and Gram-negative bacteria as well as anaerobic bacteria. Tizoxanide O-b-D-glucuronide sodium salt is also effective against mycoplasma, chlamydia, and rickettsia. This compound can be formulated in the form of a sterile powder for intravenous injection or oral administration. It is used to treat infections caused by bacteria that are resistant to other antibiotic drugs. Tizoxanide O-b-D-glucuronide sodium salt has an excellent safety profile in humans with no significant side effects reported.

Formula: C₁₆H₁₄N₃NaO₁₀S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 463.35 g/mol

Ref: 3D-MT07358