CAS 221308-01-6

L,L-Dityrosine Hydrochloride

Description:

L,L-Dityrosine Hydrochloride is a dipeptide formed from the condensation of two tyrosine molecules, characterized by the presence of two phenolic groups. This compound is typically a white to off-white crystalline powder, soluble in water and exhibiting a slightly acidic pH in solution due to the presence of the hydrochloride salt. It is known for its role in various biochemical processes, particularly in the formation of melanin and as a marker for oxidative stress in biological systems. L,L-Dityrosine Hydrochloride can also serve as a useful reagent in biochemical research, particularly in studies involving protein structure and function, as it can influence protein folding and stability. Additionally, it has potential applications in the development of biomaterials and pharmaceuticals. Its stability and reactivity make it an interesting compound for further exploration in both synthetic and natural product chemistry. As with any chemical substance, proper handling and safety precautions should be observed when working with L,L-Dityrosine Hydrochloride.

Formula: C₁₈H₂₀N₂O₆

InChI: InChI=1S/C18H20N2O6.2ClH/c19-13(17(23)24)7-9-1-3-15(21)11(5-9)12-6-10(2-4-16(12)22)8-14(20)18(25)26;;/h1-6,13-14,21-22H,7-8,19-20H2,(H,23,24)(H,25,26);2*1H/t13-,14-;;/m0../s1

InChI key: MUEPHPAGIIPFFM-AXEKQOJOSA-N

SMILES: C1=CC(=C(C=C1C[C@@H](C(=O)O)N)C2=C(C=CC(=C2)C[C@@H](C(=O)O)N)O)O.Cl.Cl

Synonyms:

• 3,3'-Dityrosine Hydrochloride
• (α3S,α3'S)-α3,α3'-DiaMino-6,6'-dihydroxy-[1,1'-biphenyl]-3,3'-dipropanoic Acid Hydrochloride
• L,L-Dityrosine dihydrochloride
• o,o'-Dityrosine Hydrochloride
• 3,3'-Bityrosine Hydrochloride
• Dityrosine Hydrochloride
• [S-(R*,R*)]- α,α'-DiaMino-6,6'-dihydroxy-[1,1'-biphenyl]-3,3'-
• (2S,2'S)-3,3'-(6,6'-dihydroxybiphenyl-3,3'-diyl)bis(2-aminopropanoic acid)
• o,o-Dityrosine Hydrochloride
• dipropanoic Acid Hydrochloride
• Bityrosine Hydrochloride

L,L-Dityrosine hydrochloride

CAS: 221308-01-6

L,L-Dityrosine hydrochloride

Formula: C₁₈H₂₂Cl₂N₂O₆

Purity: ≥98%

Molecular weight: 433.28

Ref: 54-BUP22197

L,L-Dityrosine hydrochloride

CAS: 221308-01-6

L,L-Dityrosine hydrochloride, also known as o,o'-Dityrosine hydrochloride, is a compound found in acid hydrolysates of various biological materials, notably the

Formula: C₁₈H₂₂Cl₂N₂O₆

Purity: 99.45%

Color and Shape: Brown Solid

Molecular weight: 433.283

Ref: TM-T19395

L,L-Dityrosine (hydrochloride)

CAS: 221308-01-6

Formula: C₁₈H₂₂Cl₂N₂O₆

Color and Shape: Solid

Molecular weight: 433.2831

Ref: IN-DA00C2PF

L,L-Dityrosine Dihydrochloride

Controlled Product

CAS: 221308-01-6

Stability Hygroscopic
Applications Dityrosine (DY), a tyrosine dimer formed by 3,3’-biaryl bond formation can be used as a biomarker to detect oxidative protein damage and selective proteolysis. Fluorescence intensity decays of Dityrosine are generally characterized by two decay components, one with a lifetime in the range of 150 to 800 ps and another between 2.5 and 4.5 ns.
References Libertini, L., et al.: Biophys. J., 47, 765 (1985), Huggins, T., et al.: J. Biol. Chem., 268, 12341 (1993), Malencik, D., et al.: Biochemistry, 35, 4375 (1996),

Formula: C₁₈H₂₀N₂O₆·2ClH

Color and Shape: Neat

Molecular weight: 433.28

Ref: TR-D494290

L,L-Dityrosine DiHCl

CAS: 221308-01-6

Formula: C₁₈H₂₀N₂O₆·2HCl

Molecular weight: 360.37 2*36.46

Ref: 4Z-T-144042

L,L-Dityrosine hydrochloride

CAS: 221308-01-6

Formula: C₁₈H₂₂Cl₂N₂O₆

Molecular weight: 433.3

Ref: BE-RMCT362042

L,L-Dityrosine-13C12 Dihydrochloride

Controlled Product

CAS: 221308-01-6

Formula: C₆C₁₂H₂₂Cl₂N₂O₆

Color and Shape: Neat

Molecular weight: 372.273

Ref: TR-D494293

L,L-Dityrosine dihydrochloride

CAS: 221308-01-6

Dityrosine is an amino acid derivative that has been shown to be formed by the oxidation of the amino acid L-tyrosine. It is a reactive molecule that can cause oxidative injury, as well as being involved in the pathology of various diseases such as atherosclerosis and diabetes. Dityrosine is also a potential biomarker for neuronal death, as it has been found in increased amounts in the brain tissue of patients with Alzheimer's disease. Dityrosine can be used as a tool for analyzing protein structure and enzyme activity, due to its ability to react with basic proteins and enzymes at high temperatures.

Formula: C₁₈H₂₀N₂O₆•(HCl)₂

Purity: Min. 95%

Molecular weight: 433.28 g/mol

Ref: 3D-FD22572