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CAS 221352-49-4

:

(5R)-1-(tert-butoxycarbonyl)-5-phenyl-L-proline

Description:
(5R)-1-(tert-butoxycarbonyl)-5-phenyl-L-proline, with CAS number 221352-49-4, is a chiral amino acid derivative commonly used in organic synthesis and pharmaceutical applications. This compound features a proline backbone, which is a cyclic amino acid known for its unique structural properties that influence peptide conformation. The tert-butoxycarbonyl (Boc) group serves as a protecting group for the amino functionality, facilitating selective reactions without interfering with the proline's reactivity. The presence of the phenyl group at the 5-position enhances the compound's hydrophobic character, which can influence its solubility and interaction with biological systems. As a chiral molecule, it exists in two enantiomeric forms, with the (5R) configuration being biologically relevant in various applications, including drug design and synthesis of peptide-based therapeutics. Overall, this compound is significant in the field of medicinal chemistry, particularly in the development of compounds with specific stereochemical properties for targeted biological activity.
Formula:C16H21NO4
InChI:InChI=1/C16H21NO4/c1-16(2,3)21-15(20)17-12(9-10-13(17)14(18)19)11-7-5-4-6-8-11/h4-8,12-13H,9-10H2,1-3H3,(H,18,19)/t12-,13+/m1/s1
Synonyms:
  • (2S,5R)-Boc-5-Phenyl-Pyrrolidine-2-Carboxylic Acid
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