CAS 22144-77-0

(-)-Cytochalasin D

Description:

(-)-Cytochalasin D is a naturally occurring alkaloid derived from various species of fungi, particularly from the genus *Helminthosporium*. It is known for its ability to inhibit actin polymerization, which plays a crucial role in various cellular processes, including cell division, motility, and shape maintenance. The compound exhibits a complex structure characterized by a lactone ring and multiple functional groups, contributing to its biological activity. As a potent cytoskeletal disruptor, (-)-Cytochalasin D has been extensively studied for its effects on cell morphology and movement, making it a valuable tool in cell biology research. It is often used in laboratory settings to investigate the dynamics of the cytoskeleton and its implications in various physiological and pathological processes. Additionally, due to its biological properties, (-)-Cytochalasin D has potential applications in cancer research and therapeutic development, although its use is limited by its toxicity and the need for careful handling in experimental contexts.

Formula: C₃₀H₃₇NO₆

InChI: InChI=1/C30H37NO6/c1-17-10-9-13-22-26(33)19(3)18(2)25-23(16-21-11-7-6-8-12-21)31-28(35)30(22,25)24(37-20(4)32)14-15-29(5,36)27(17)34/h6-9,11-15,17-18,22-26,33,36H,3,10,16H2,1-2,4-5H3,(H,31,35)/b13-9-,15-14-/t17-,18+,22-,23-,24+,25-,26+,29+,30?/m1/s1

InChI key: InChIKey=SDZRWUKZFQQKKV-JHADDHBZSA-N

SMILES: O(C(C)=O)[C@H]/1[C@]23[C@]([C@H](CC4=CC=CC=C4)NC2=O)([C@H](C)C(=C)[C@@H](O)[C@@]3(/C=C/C[C@H](C)C(=O)[C@](C)(O)\C=C1)[H])[H]

Synonyms:

• (3R,3aS,4R,6R,6aS,7Z,10R,12S,13Z,15S)-3-benzyl-6,12-dihydroxy-4,10,12-trimethyl-5-methylidene-1,11-dioxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate
• (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-15-(Acetyloxy)-3,3a,4,5,6,6a,9,10,12,15-decahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-1H-cycloundec[d]isoindole-1,11(2H)-dione
• (7E,13E)-3-benzyl-6,12-dihydroxy-4,10,12-trimethyl-5-methylidene-1,11-dioxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate
• (7E,13Z)-3-benzyl-6,12-dihydroxy-4,10,12-trimethyl-5-methylidene-1,11-dioxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate
• 1H-Cycloundec[d]isoindole-1,11(2H)-dione, 15-(acetyloxy)-3,3a,4,5,6,6a,9,10,12,15-decahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-, (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-
• 1H-Cycloundec[d]isoindole-1,11(2H)-dione, 15-(acetyloxy)-3,3a,4,5,6,6a,9,10,12,15-decahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-, [3S-(3R*,3aS*,4R*,6R*,6aS*,7E,10R*,12S*,13E,15S*,15aS*)]-
• 3-benzyl-6,12-dihydroxy-4,10,12-trimethyl-5-methylidene-1,11-dioxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate
• Cytochalasin D, Zygusporium mansonii
• NSC 209835
• Zygosporin A
• [11]Cytochalasa-6(12),13,19-triene-1,17-dione, 21-(acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl-, (7S,13E,16S,18R,19E,21R)-
• cytochalasin D
• 1h-cycloundec(d)isoindole-1,11(2h)-dione,3-benzyl-3,3-alpha,4,5,6,6-alpha,9,10
• CYTOCHALASIN D(RG)
• (7S,13E,16S,18R,19E,21R)-21-(ACETYLOXY)-7,18-DIHYDROXY-16,18-DIMETHYL-10-PHENYL[11]CYTOCHALASA-6(12),13,19-TRIENE-1,17-DIONE
• cytochalasin D from zygosporium masonii
• (11)cytochalasa-6(12),13,19-triene-1,17-dione,21-(acetyloxy)-7,18-dihydroxy-16
• Nsc209835
• CYTOCHALICIND
• Cytohalasin d
• CYTOCHALACIND
• Cytochalasin D, Zygosporin A
• 1H-Cycloundecdisoindole-1,11(2H)-dione, 15-(acetyloxy)-3,3a,4,5,6,6a,9,10,12,15-decahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-, (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-
• CYTOCHALASIN D FROM ZYGOSPORIUMMANSONII
• 7(S),18(R)-dihydroxy-16(S),18-dimethyl-10-phenyl[11]cytochalasa-6(12),13(E),19(E)-triene-1,17-dione 21(R)-acetate
• [11]Cytochalasa-6[12],13,19-triene-1,17-dione, 21-(acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl-
• 1h-cycloundec(d)isoindole-1,11(2h)-dione,3-benzyl-3,3-alpha4,5,6,6-alpha,9,10,
• CYTOCHALASIN D, ZYGOSPORIUM MANSONII
• ,12,15-decahydro-6,12,15-trihydroxy-4,10,12-trimethyl-5-methylene-,15-acetate
• Lygosporin a
• ,18-dimethyl-10-phenyl-,(7s,13e,16s,18r,19e,21r)-
• 1H-Cycloundec[D]isoindole-1,11(2H)-dione, 3-benzyl-3,3-.alpha.,4,5,6,6-.alpha.,9,10,12,15-decahydro-6,12,15-trihydroxy-4,10,12-trimethyl-5-methylene-, 15-acetate
• 7,18-dihydroxy-10-phenyl-5,16,18-trimethyl-[11]cytochalas-21-acetoxy-6(12),13,
• 15-decahydro-6,12,15-trihydroxy-4,10,12-trimethyl-5-methylene-115-acetate
• InSolution? Cytochalasin D,

Cytochalasin D

CAS: 22144-77-0

Cytochalasin D

Formula: C₃₀H₃₇NO₆

Purity: By hplc: 99.79% (Typical Value in Batch COA)

Color and Shape: white powder

Molecular weight: 507.61787g/mol

Ref: 54-BIC1016

Cytochalasin D

CAS: 22144-77-0

Formula: C₃₀H₃₇NO₆

Purity: ≥ 97.0%

Color and Shape: White powder

Molecular weight: 507.62

Ref: 7W-GA1531

Cytochalasin D

CAS: 22144-77-0

Cytochalasin D inhibits actin, chondrogenesis, fertilization, tumor growth, and phagocytosis; may increase B16 melanoma metastasis.

Formula: C₃₀H₃₇NO₆

Purity: 99.586%

Color and Shape: Needles From Acetone-Petroleum Ether Physical Description Needles Or Fluffy White Powder (Ntp 1992)

Molecular weight: 507.62

Ref: TM-T3229

Cytochalasin D

CAS: 22144-77-0

Formula: C₃₀H₃₇NO₆

Purity: 95%~99%

Molecular weight: 507.627

Ref: BP-SBP60020

Cytochalasin D

CAS: 22144-77-0

Inhibits actin polymerization

Formula: C₃₀H₃₇NO₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 507.62 g/mol

Ref: 3D-FC29349