CAS 22145-68-2

25-Hydroxy-7-dehydrocholesterol

Description:

25-Hydroxy-7-dehydrocholesterol, with the CAS number 22145-68-2, is a sterol compound that plays a significant role in the biosynthesis of vitamin D. It is a derivative of cholesterol, characterized by the presence of a hydroxyl group at the 25th carbon position and a double bond between the 7th and 8th carbons. This compound is typically found in the human body and is produced in the liver from 7-dehydrocholesterol, which is then converted to vitamin D3 upon exposure to ultraviolet light. 25-Hydroxy-7-dehydrocholesterol is often measured in clinical settings to assess vitamin D status, as it serves as a key biomarker for evaluating the body's vitamin D levels. The compound is lipophilic, allowing it to integrate into cellular membranes and interact with various biological processes. Its stability and solubility characteristics make it relevant in both biological and pharmaceutical contexts, particularly in the study of metabolic pathways related to cholesterol and vitamin D synthesis.

Formula: C₂₇H₄₄O₂

InChI: InChI=1S/C27H44O2/c1-18(7-6-14-25(2,3)29)22-10-11-23-21-9-8-19-17-20(28)12-15-26(19,4)24(21)13-16-27(22,23)5/h8-9,18,20,22-24,28-29H,6-7,10-17H2,1-5H3/t18-,20+,22-,23+,24+,26+,27-/m1/s1

InChI key: InChIKey=JJFYNCJHSCTBPW-TVQCKQBJSA-N

SMILES: C[C@@]12[C@](C=3[C@@]([C@]4(C)C(=CC3)C[C@@H](O)CC4)(CC1)[H])(CC[C@@]2([C@@H](CCCC(C)(C)O)C)[H])[H]

Synonyms:

• 7-Dehydro-25-hydroxycholesterol
• 25-Hydroxy-7-dehydrocholesterol
• (3β)-Cholesta-5,7-diene-3,25-diol
• Cholesta-5,7-diene-3β,25-diol
• Cholesta-5,7-diene-3,25-diol, (3β)-
• (3S,9S,10R,13R,14R,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol
• Calcifediol Impurity 2（Calcifediol EP Impurity B）
• Calcifediol EP Impurity B/Cholesta-5,7-diene-3β,25-dio
• 25-HydroxyprovitaMin D3
• Calcifediol EP Impurity B
• IMpurity B of Calcifediol

Calcifediol EP Impurity B

CAS: 22145-68-2

Formula: C₂₇H₄₄O₂

Molecular weight: 400.65

Ref: 4Z-C-273003

25-Hydroxyprovitamin D3-d6

Controlled Product

CAS: 22145-68-2

Applications 25-Hydroxyprovitamin D3-d6 is labelled 25-Hydroxyprovitamin D3 (H950940), an impurity of Calcifediol (C125700) which is a metabolite of Vitamin D.
References Morii, et al.: Arch. Biochem. Biophys., 120, 513 (1967); Blunt, et al.: Biochemistry, 7, 3317 (1968;, Liu, et al.: Science, 311, 1770 (2006)

Formula: C₂₇D₆H₃₈O₂

Color and Shape: Neat

Molecular weight: 406.674

Ref: TR-H950942

25-Hydroxyprovitamin D3

Controlled Product

CAS: 22145-68-2

Impurity Chloesterol Impurity 6
Applications 25-Hydroxyprovitamin D3 (Chloesterol Impurity 6) is an impurity of Calcifediol (C125700) which is a metabolite of Vitamin D.
References Morii, et al.: Arch. Biochem. Biophys., 120, 513 (1967); Blunt, et al.: Biochemistry, 7, 3317 (1968;, Liu, et al.: Science, 311, 1770 (2006)

Formula: C₂₇H₄₄O₂

Color and Shape: Neat

Molecular weight: 400.637

Ref: TR-H950940

Calcifediol EP Impurity B

CAS: 22145-68-2

Formula: C₂₇H₄₄O₂

Molecular weight: 400.65

Ref: ST-EA-CP-C167002