CAS 2216-51-5

(-)-Menthol

Description:

(-)-Menthol, with the CAS number 2216-51-5, is a naturally occurring compound classified as a monoterpene alcohol. It is primarily derived from peppermint and other mint oils, contributing to their characteristic aroma and flavor. This compound exists in several stereoisomeric forms, with the (-)-enantiomer being the most prevalent and biologically active. (-)-Menthol is known for its cooling sensation, which is a result of its interaction with the TRPM8 receptor, making it widely used in products such as topical analgesics, oral hygiene products, and confectionery. It is a colorless to pale yellow liquid at room temperature, with a characteristic minty odor. (-)-Menthol is soluble in alcohol and oils but has limited solubility in water. Additionally, it exhibits antimicrobial properties and has been studied for its potential therapeutic effects, including anti-inflammatory and analgesic activities. Its versatility and pleasant sensory attributes make it a valuable ingredient in various industries, including pharmaceuticals, cosmetics, and food.

Formula: C₁₀H₂₀O

InChI: InChI=1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3/t8-,9+,10-/m1/s1

InChI key: InChIKey=NOOLISFMXDJSKH-KXUCPTDWSA-N

SMILES: [C@H](C)(C)[C@H]1[C@H](O)C[C@H](C)CC1

Synonyms:

• (-)-(1R,3R,4S)-Menthol
• (-)-Menthol
• (-)-Menthyl alcohol
• (-)-Paramenthol-3
• (-)-trans-p-Menthan-cis-3-ol
• (-)-trans-p-Methan-cis-3-ol
• (1R)-(-)-Menthol
• (1R,2R,5R)-5-methyl-2-(propan-2-yl)cyclohexanol
• (1R,2S,5R)-(-)-Menthol
• (1R,2S,5R)-2-Isopropyl-5-methylcyclohexan-1-ol
• (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol
• (1R,2S,5R)-5-Methyl-2-(propan-2-yl)cyclohexanol
• (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexanol
• (R)-(-)-Menthol
• <span class="text-smallcaps">L</span>-Menthol
• A 10474
• CYCLOHEXANOL, 5-METHYL-2(1-METHYLETHYL)-, [1R-(1α, 2β, 5α)]-
• Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1R,2S,5R)-
• Cyclohexanol, 5-methyl-2-(1-methylethyl)-, [1R-(1α,2β,5.alpha]).-
• D-(-)-Menthol
• Fema 2665
• Hakkano
• Hexahydrothymol
• L-Menthol natural
• L-Mentholum
• L-mentol
• L-p-Menthan-3-ol
• Levomenthol
• Menthol, (1R,3R,4S)-(-)-
• Menthol, L-
• Menthol, Levo-
• Methylhydroxyisopropylcyclohexane
• Minclea
• Nsc 62788
• l-Menthol

L-Menthol

CAS: 2216-51-5

L-Menthol is a crystalline solid that has antifungal properties. It is used in pharmaceuticals, cosmetics, and food products. L-Menthol is produced from the plant Mentha arvensis. The reaction mechanism of L-menthol with benzalkonium chloride has been shown to inhibit the growth of Hl-60 cells in vitro and to demonstrate potent antifungal activity against Candida albicans isolates. L-Menthol can be extracted from Mentha arvensis by solid phase microextraction on a polymeric membrane using an organic solvent as the extracting agent. The extract is then purified by crystallization or column chromatography. This process can also be used for other compounds, such as l-menthol, which are chemically related to menthol. L-Menthol has been shown to have chemopreventive effects against colorectal adenocarcinoma in rats and inhibits platelet aggregation

Formula: C₁₀H₂₀O

Purity: Min. 95%

Color and Shape: Colorless Powder

Molecular weight: 156.27 g/mol

Ref: 3D-FM44476