CAS 2216-51-5: (-)-Menthol

Description: (-)-Menthol, with the CAS number 2216-51-5, is a naturally occurring compound classified as a monoterpene alcohol. It is primarily derived from peppermint and other mint oils, contributing to their characteristic aroma and flavor. This compound exists in several stereoisomeric forms, with the (-)-enantiomer being the most prevalent and biologically active. (-)-Menthol is known for its cooling sensation, which is a result of its interaction with the TRPM8 receptor, making it widely used in products such as topical analgesics, oral hygiene products, and confectionery. It is a colorless to pale yellow liquid at room temperature, with a characteristic minty odor. (-)-Menthol is soluble in alcohol and oils but has limited solubility in water. Additionally, it exhibits antimicrobial properties and has been studied for its potential therapeutic effects, including anti-inflammatory and analgesic activities. Its versatility and pleasant sensory attributes make it a valuable ingredient in various industries, including pharmaceuticals, cosmetics, and food.

Formula: C₁₀H₂₀O

InChI: InChI=1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3/t8-,9+,10-/m1/s1

InChI key: InChIKey=NOOLISFMXDJSKH-KXUCPTDWSA-N

SMILES: OC1CC(C)CCC1C(C)C

Synonyms:

• (-)-(1R,3R,4S)-Menthol
• (-)-Menthol
• (-)-Menthyl alcohol
• (-)-Paramenthol-3
• (-)-trans-p-Menthan-cis-3-ol
• (-)-trans-p-Methan-cis-3-ol
• (1R)-(-)-Menthol
• (1R,2R,5R)-5-methyl-2-(propan-2-yl)cyclohexanol
• (1R,2S,5R)-(-)-Menthol
• (1R,2S,5R)-2-Isopropyl-5-methylcyclohexan-1-ol
• (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol
• (1R,2S,5R)-5-Methyl-2-(propan-2-yl)cyclohexanol
• (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexanol
• (R)-(-)-Menthol
• <span class="text-smallcaps">L</span>-Menthol
• A 10474
• CYCLOHEXANOL, 5-METHYL-2(1-METHYLETHYL)-, [1R-(1α, 2β, 5α)]-
• Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1R,2S,5R)-
• Cyclohexanol, 5-methyl-2-(1-methylethyl)-, [1R-(1α,2β,5.alpha]).-
• D-(-)-Menthol
• Fema 2665
• Hakkano
• Hexahydrothymol
• L-Menthol natural
• L-Mentholum
• L-mentol
• L-p-Menthan-3-ol
• Levomenthol
• Menthol, (1R,3R,4S)-(-)-
• Menthol, L-
• Menthol, Levo-
• Methylhydroxyisopropylcyclohexane
• Minclea
• Nsc 62788
• l-Menthol
• L-Menthol

Natural menthol

CAS: 2216-51-5

Natural

• Purity: Min. 95%