CAS 22160-09-4

(-)-2-Methylindoline

Description:

(-)-2-Methylindoline is an organic compound characterized by its bicyclic structure, which consists of a fused indole and a methyl group at the second position. This compound is a chiral molecule, with the "(-)" designation indicating its specific stereochemistry, which can influence its biological activity and interactions. It typically appears as a colorless to pale yellow liquid or solid, depending on its purity and form. (-)-2-Methylindoline is known for its potential applications in pharmaceuticals and organic synthesis, particularly in the development of various biologically active compounds. Its properties include moderate solubility in organic solvents and relatively low solubility in water, which is common for many indole derivatives. The compound's reactivity can be attributed to the presence of the indole nitrogen, which can participate in various chemical reactions, including electrophilic substitutions and nucleophilic additions. As with many organic compounds, safety precautions should be taken when handling (-)-2-Methylindoline, as it may pose health risks if ingested or inhaled.

Formula: C₉H₁₁N

InChI: InChI=1S/C9H11N/c1-7-6-8-4-2-3-5-9(8)10-7/h2-5,7,10H,6H2,1H3/t7-/m0/s1

InChI key: InChIKey=QRWRJDVVXAXGBT-ZETCQYMHSA-N

SMILES: C[C@H]1CC=2C(N1)=CC=CC2

Synonyms:

• (2S)-2,3-Dihydro-2-methyl-1H-indole
• 1H-Indole, 2,3-dihydro-2-methyl-, (S)-
• 1H-Indole, 2,3-dihydro-2-methyl-, (2S)-
• (-)-2-Methylindoline
• Indoline, 2-methyl-, (-)-

(2S)-2,3-dihydro-2-Methyl-1H-Indole

CAS: 22160-09-4

Formula: C₉H₁₁N

Purity: 95%

Color and Shape: Liquid

Molecular weight: 133.1903

Ref: IN-DA006ZTD

(2S)-2-Methyl-2,3-dihydro-1H-indole

CAS: 22160-09-4

(2S)-2-Methyl-2,3-dihydro-1H-indole

Molecular weight: 133.19034g/mol

Ref: 54-OR1020676

Indapamide Impurity 18

CAS: 22160-09-4

Formula: C₉H₁₁N

Color and Shape: Off-White Solid

Molecular weight: 133.19

Ref: 4Z-I-1332

(2S)-2,3-DIHYDRO-2-METHYL-1H-INDOLE

CAS: 22160-09-4

Formula: C₉H₁₁N

Purity: 97%

Molecular weight: 133.194

Ref: 10-F334325

(2S)-2-methyl-2,3-dihydro-1H-indole

CAS: 22160-09-4

(2S)-2-methyl-2,3-dihydro-1H-indole is a synthetic antipsychotic drug. It is an atypical antipsychotic drug that has been shown to be effective in the treatment of schizophrenia. The antipsychotic efficacy of this compound may be due to its ability to bind with serotonin receptors and inhibit the reuptake of dopamine. (2S)-2-methyl-2,3-dihydro-1H-indole binds more selectively to dopamine D4 receptors than other dopamine receptors. This compound was synthesized by diazotation, followed by selective reduction with hexafluoroisopropanol, and then asymmetric synthesis with piperazine and d4 as reactants.

Formula: C₉H₁₁N

Purity: Min. 95%

Molecular weight: 133.19 g/mol

Ref: 3D-XAA16009