CAS 2216712-66-0: Elexacaftor

Description:Elexacaftor is a small molecule drug primarily used in the treatment of cystic fibrosis, particularly in patients with specific mutations in the CFTR gene. It functions as a CFTR modulator, enhancing the processing and function of the CFTR protein, which is crucial for maintaining the balance of salt and water on epithelial surfaces. Elexacaftor is often used in combination with other CFTR modulators, such as tezacaftor and ivacaftor, to improve therapeutic efficacy. The substance is characterized by its ability to increase the quantity of functional CFTR protein at the cell surface, thereby improving chloride transport and alleviating symptoms associated with cystic fibrosis. Elexacaftor is administered orally and has been shown to improve lung function and reduce pulmonary exacerbations in patients. Its chemical structure includes specific functional groups that contribute to its activity and pharmacokinetic properties, making it a vital component in the management of cystic fibrosis. As with any medication, potential side effects and contraindications should be considered, and it is essential to follow medical guidance when using this drug.

Synonyms:
Elexacaftor VX-445
N-(1,3-dimethylpyrazol-4-yl)sulfonyl-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)pyrazol-1-yl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide
3-Pyridinecarboxamide, N-[(1,3-dimethyl-1H-pyrazol-4-yl)sulfonyl]-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl]-2-[(4S)-2,2,4-trimethyl-1-pyrrolidinyl]-

Found 9 products.

Product data	Purity	Price range	Estimated delivery
Elexacaftor REF: TM-T14935CAS: 2216712-66-0	98.87% - 99.87%	87.00 €~1,444.00 €	Mon 14 Apr 25
Elexacaftor REF: IN-DA01KXYXCAS: 2216712-66-0	98%	To inquire	Mon 14 Apr 25
Elexacaftor REF: 54-BUP04170CAS: 2216712-66-0	99.87%	1,131.00 €~1,955.00 €	Tue 15 Apr 25
Elexacaftor REF: 4Z-E-169001CAS: 2216712-66-0	- - -	To inquire	Tue 15 Apr 25
(S)-N-((1,3-Dimethyl-1H-Pyrazol-4-Yl)Sulfonyl)-6-(3-(3,3,3-Trifluoro-2,2-Dimethylpropoxy)-1H-Pyrazol-1-Yl)-2-(2,2,4-Trimethylpyrrolidin-1-Yl)Nicotinamide REF: 54-PC108563CAS: 2216712-66-0	- - -	516.00 €	Tue 15 Apr 25
Elexacaftor-13C-d3 REF: 4Z-E-169002CAS: 2216712-66-0	- - -	To inquire	Mon 21 Apr 25
Elexacaftor REF: TR-E201545CAS: 2216712-66-0	- - -	361.00 €~2,473.00 €	Thu 24 Apr 25
Elexacaftor-D3 REF: TR-E201547CAS: 2216712-66-0	- - -	604.00 €~4,041.00 €	Thu 24 Apr 25
Elexacaftor REF: 3D-FE178668CAS: 2216712-66-0	95%Min	373.00 €~8,093.00 €	Mon 23 Jun 25