CAS 2216712-66-0

Elexacaftor

Description:

Elexacaftor is a small molecule drug primarily used in the treatment of cystic fibrosis, particularly in patients with specific mutations in the CFTR gene. It functions as a CFTR modulator, enhancing the processing and function of the CFTR protein, which is crucial for maintaining the balance of salt and water on epithelial surfaces. Elexacaftor is often used in combination with other CFTR modulators, such as tezacaftor and ivacaftor, to improve therapeutic efficacy. The substance is characterized by its ability to increase the quantity of functional CFTR protein at the cell surface, thereby improving chloride transport and alleviating symptoms associated with cystic fibrosis. Elexacaftor is administered orally and has been shown to improve lung function and reduce pulmonary exacerbations in patients. Its chemical structure includes specific functional groups that contribute to its activity and pharmacokinetic properties, making it a vital component in the management of cystic fibrosis. As with any medication, potential side effects and contraindications should be considered, and it is essential to follow medical guidance when using this drug.

Synonyms:

• Elexacaftor VX-445
• N-(1,3-dimethylpyrazol-4-yl)sulfonyl-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)pyrazol-1-yl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide
• 3-Pyridinecarboxamide, N-[(1,3-dimethyl-1H-pyrazol-4-yl)sulfonyl]-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl]-2-[(4S)-2,2,4-trimethyl-1-pyrrolidinyl]-

Elexacaftor

CAS: 2216712-66-0

Elexacaftor (VX-445) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector.Cost-effective and quality-assured.

Formula: C₂₆H₃₄F₃N₇O₄S

Purity: 98.87% - 99.87%

Color and Shape: Solid

Molecular weight: 597.65

Ref: TM-T14935

Elexacaftor

CAS: 2216712-66-0

Formula: C₂₆H₃₄F₃N₇O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 597.6529

Ref: IN-DA01KXYX

Elexacaftor

CAS: 2216712-66-0

Elexacaftor

Purity: ≥98%

Molecular weight: 597.65g/mol

Ref: 54-BUP04170

Elexacaftor

CAS: 2216712-66-0

Formula: C₂₆H₃₄F₃N₇O₄S

Molecular weight: 597.66

Ref: 4Z-E-169001

(S)-N-((1,3-Dimethyl-1H-Pyrazol-4-Yl)Sulfonyl)-6-(3-(3,3,3-Trifluoro-2,2-Dimethylpropoxy)-1H-Pyrazol-1-Yl)-2-(2,2,4-Trimethylpyrrolidin-1-Yl)Nicotinamide

CAS: 2216712-66-0

(S)-N-((1,3-Dimethyl-1H-Pyrazol-4-Yl)Sulfonyl)-6-(3-(3,3,3-Trifluoro-2,2-Dimethylpropoxy)-1H-Pyrazol-1-Yl)-2-(2,2,4-Trimethylpyrrolidin-1-Yl)Nicotinamide

Purity: 99%

Molecular weight: 597.65g/mol

Ref: 54-PC108563

Elexacaftor-13C-d3

CAS: 2216712-66-0

Formula: C₂₅₁₃CH₃₁D₃F₃N₇O₄S

Molecular weight: 601.67

Ref: 4Z-E-169002

Elexacaftor

CAS: 2216712-66-0

Formula: C₂₆H₃₄F₃N₇O₄S

Color and Shape: White To Off-White

Molecular weight: 597.65

Ref: TR-E201545

Elexacaftor-D3

Controlled Product

CAS: 2216712-66-0

Formula: C₂₆D₃H₃₁F₃N₇O₄S

Color and Shape: Neat

Molecular weight: 600.671

Ref: TR-E201547

Elexacaftor

CAS: 2216712-66-0

Please enquire for more information about Elexacaftor including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₂₆H₃₄F₃N₇O₄S

Purity: 95%Min

Molecular weight: 597.65 g/mol

Ref: 3D-FE178668