CAS 221681-92-1

1,3-dimethyl-1H-indazol-6-amine

Description:

1,3-Dimethyl-1H-indazol-6-amine is a chemical compound characterized by its indazole core, which is a five-membered heterocyclic structure containing two nitrogen atoms. This compound features two methyl groups attached to the first carbon of the indazole ring and an amino group at the sixth position. It is typically a solid at room temperature and may exhibit moderate solubility in polar organic solvents. The presence of the amino group suggests potential for hydrogen bonding, which can influence its reactivity and interactions with other molecules. This compound is of interest in various fields, including medicinal chemistry, due to its potential biological activity. It may serve as a scaffold for the development of pharmaceuticals or as a research tool in studying biological pathways. Safety and handling precautions should be observed, as with any chemical substance, to mitigate risks associated with exposure. Overall, 1,3-dimethyl-1H-indazol-6-amine represents a versatile structure with implications in chemical research and development.

Formula: C₉H₁₁N₃

InChI: InChI=1S/C9H11N3/c1-6-8-4-3-7(10)5-9(8)12(2)11-6/h3-5H,10H2,1-2H3

InChI key: InChIKey=VGABHBLCCIOEOZ-UHFFFAOYSA-N

SMILES: CN1C=2C(C(C)=N1)=CC=C(N)C2

Synonyms:

• 1,3-Dimethyl-1H-indazol-6-ylamine
• 1,3-dimethyl-1H-indazol-6-amine
• 1,3-DiMethyl-6-aMino-1H-indazole
• 1,3-Dimethylindazol-6-amine
• Pazopanib Impurity 17
• 1H-Indazol-6-amine, 1,3-dimethyl-
• 1,3-DiMethyl-6-aMino-1H-i...

1,3-DIMETHYL-6-AMINO-1H-INDAZOLE

CAS: 221681-92-1

Formula: C₉H₁₁N₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 161.2037

Ref: IN-DA00CGCM

Pazopanib Impurity 3

CAS: 221681-92-1

Formula: C₁₀H₁₃N₂

Color and Shape: Pale Pink Solid

Molecular weight: 161.21

Ref: 4Z-P-129013

1,3-Dimethyl-6-amino-1H-indazole

CAS: 221681-92-1

1,3-Dimethyl-6-amino-1H-indazole

Molecular weight: 161.20374g/mol

Ref: 54-OR1020912

1,3-Dimethylindazol-6-amine

Controlled Product

CAS: 221681-92-1

Formula: C₉H₁₁N₃

Color and Shape: Neat

Molecular weight: 161.20

Ref: 86-MM3391.03

1,3-Dimethyl-6-amino-1H-indazole

CAS: 221681-92-1

Formula: C₉H₁₁N₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 161.208

Ref: 10-F468239

1,3-dimethyl-1H-indazol-6-amine

Controlled Product

CAS: 221681-92-1

Applications 1,3-dimethyl-1H-indazol-6-amine is an impurity in the synthesis of Pazopanib (P210925) which is an oral angiogenesis inhibitor targeting VEGFR and PDGFR. It is used as a reagent in the preparation of glycinamide derivatives which are useful in production of drugs for preventing and treating diseases caused by S-adenosyl homocysteine hydrolase.
References Olaussen, K., et al.: Oncogen., 28, 4249 (2009); Sleijfer, S., et al.: J. Clin. Oncol., 27, 3126 (2009); Chan, A., et al.: Drugs, 69, 167 (2009); Tan, X., et al.: China Patent 104277002, Jan 14, 2015;

Formula: C₉H₁₁N₃

Color and Shape: Neat

Molecular weight: 161.20

Ref: TR-D474120

1,3-Dimethyl-6-amino-1H-indazole

CAS: 221681-92-1

1,3-Dimethyl-6-amino-1H-indazole is a hydrogen bond donor and the skeleton is planar. It has been shown to be a potential drug for the treatment of neurodegenerative diseases.

Formula: C₉H₁₁N₃

Purity: Min. 95%

Molecular weight: 161.2 g/mol

Ref: 3D-WIA68192

Pazopanib Impurity 6

CAS: 221681-92-1

Formula: C₁₀H₁₃N₂

Molecular weight: 161.2

Ref: ST-EA-CP-P58022