CAS 2220162-06-9

NMDAR antagonist 1

CAS: 2220162-06-9

Formula: C₂₀H₂₀BrN₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 414.2957

Ref: IN-DA01KL19

NMDAR antagonist 1

CAS: 2220162-06-9

NMDAR antagonist 1

Purity: ≥95%

Molecular weight: 414.3g/mol

Ref: 54-BUP04953

NMDAR antagonist 1

CAS: 2220162-06-9

NMDAR antagonist 1 is an orally active, NR2B-selective NMDAR antagonist.

Formula: C₂₀H₂₀BrN₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 414.3

Ref: TM-T5522

NMDAR antagonist 1

CAS: 2220162-06-9

NMDAR antagonist 1 is a chemical compound that functions as a non-competitive antagonist at the N-methyl-D-aspartate receptor (NMDAR), a subtype of glutamate receptor. Sourced synthetically, this compound is designed to modify neurotransmitter activity in the central nervous system by inhibiting the action of glutamate, which is the primary excitatory neurotransmitter. Its mode of action involves blocking the ion channel of the NMDAR, thereby preventing calcium ions from entering the neuron and modulating synaptic plasticity and neuronal communication.

This antagonist is widely used in neuroscience research to study the mechanisms of excitotoxicity, which is implicated in a variety of neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). It is also utilized to explore the fundamental processes involving learning, memory, and synaptic transmission. By providing insights into glutamatergic signaling pathways, NMDAR antagonist 1 aids in the development of therapeutic strategies for conditions related to excessive neuronal activity and synaptic dysfunction.

Formula: C₂₀H₂₀BrN₃O₂

Purity: Min. 95%

Molecular weight: 414.3 g/mol

Ref: 3D-VND16206