CAS 22204-24-6: Pyrantel pamoate
Description:Pyrantel pamoate is an anthelmintic medication primarily used to treat infections caused by various intestinal parasites, including roundworms and hookworms. It functions by causing paralysis of the parasites, allowing them to be expelled from the host's body. The compound is a salt formed from pyrantel, a derivative of the tetrahydropyrimidine class, and pamoic acid. Pyrantel pamoate is typically administered orally and is known for its relatively low toxicity, making it suitable for use in both adults and children. It is poorly absorbed in the gastrointestinal tract, which enhances its effectiveness against intestinal parasites while minimizing systemic side effects. The substance is often available in various formulations, including suspensions and tablets, and is commonly used in veterinary medicine as well. Its mechanism of action involves the inhibition of neuromuscular transmission in the parasites, leading to their paralysis and subsequent elimination. Overall, pyrantel pamoate is a valuable agent in the management of parasitic infections.
Formula:C23H16O6·C11H14N2S
InChI:InChI=1S/C23H16O6.C11H14N2S/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2,4-6,9H,3,7-8H2,1H3/b;6-5+
InChI key:InChIKey=AQXXZDYPVDOQEE-MXDQRGINSA-N
SMILES:O=C(O)C1=CC=2C=CC=CC2C(=C1O)CC3=C(O)C(=CC=4C=CC=CC43)C(=O)O.N1=C(C=CC=2SC=CC2)N(C)CCC1
- Synonyms:
- 1,4,5,6-tetrahydro-1-methyl-2-((E)-2-(2-thienyl)vinyl)pyrimidine 4,4'-methylenebis(3-hydroxy-2-naphthoate)
- 2-Naphthalenecarboxylic acid, 4,4′-methylenebis[3-hydroxy-, compd. with (E)-1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)ethenyl]pyrimidine (1:1)
- 2-Naphthalenecarboxylic acid, 4,4′-methylenebis[3-hydroxy-, compd. with 1,4,5,6-tetrahydro-1-methyl-2-[(1E)-2-(2-thienyl)ethenyl]pyrimidine (1:1)
- 2-Naphthoic acid, 4,4′-methylenebis[3-hydroxy-, compd. with (E)-1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]pyrimidine (1:1)
- 2-Naphthoicacid,4,4'-Methylenebis(3-Hydroxy-,Compd.With(E)-1,4,5,6-Tetrahy
- 4,4'-Methanediylbis(3-Hydroxynaphthalene-2-Carboxylic Acid) - 1-Methyl-2-[2-(Thiophen-2-Yl)Ethenyl]-1,4,5,6-Tetrahydropyrimidine (1:1)
- 4,4'-methylenebis(3-hydroxy-2-naphthoic acid) compounded with (E)-1,4,5,6-tetrahydro-1-methyl-2-(2-(2-thienyl)vinyl)pyrimidine (1:1)
- Antiminth
- Cobantril
- Combantrin
- See more synonyms
- Cp-10423-16
- Dog Wormer
- Early Bird
- Embovin
- Helmex
- Helmintox
- Lombriareu
- Nemocid
- Pirantel Pamoate
- Piranver
- Pyrantel Embonate
- Pyrantel Pamoate
- Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-[(1E)-2-(2-thienyl)ethenyl]-, 4,4′-methylenebis[3-hydroxy-2-naphthalenecarboxylate] (1:1)
- Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)ethenyl]-, (E)-, 4,4′-methylenebis[3-hydroxy-2-naphthalenecarboxylate] (1:1)
- Trilombrin
