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CAS 22204-53-1

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Naproxen

Description:
Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to relieve pain, reduce inflammation, and lower fever. It is characterized by its ability to inhibit the enzyme cyclooxygenase (COX), which plays a crucial role in the synthesis of prostaglandins, compounds involved in inflammation and pain signaling. Naproxen is typically administered in its sodium salt form, enhancing its solubility and absorption. The substance is known for its relatively long half-life, allowing for less frequent dosing compared to some other NSAIDs. It is often used to treat conditions such as arthritis, menstrual pain, and other acute pain scenarios. Common side effects may include gastrointestinal discomfort, headache, and dizziness, while more serious risks involve cardiovascular and gastrointestinal complications. Naproxen is contraindicated in certain populations, such as individuals with specific allergies or pre-existing health conditions. As with all medications, it is essential to use naproxen under the guidance of a healthcare professional to ensure safety and efficacy.
Formula:C14H14O3
InChI:InChI=1/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/p-1/t9-/m0/s1
InChI key:InChIKey=CMWTZPSULFXXJA-VIFPVBQESA-N
SMILES:[C@H](C(O)=O)(C)C1=CC2=C(C=C(OC)C=C2)C=C1
Synonyms:
  • (+)-(S)-Naproxen
  • (+)-2-(6-Methoxy-2-naphthyl)propionic acid
  • (+)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid
  • (+)-6-Methoxy-α-methyl-2-naphthaleneacetic acid
  • (2S)-2-(6-Methoxy-2-naphthyl)propanoic acid
  • (2S)-2-(6-methoxynaphthalen-2-yl)propanoate
  • (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid
  • (S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid
  • (S)-(+)-Naproxene
  • (S)-2-(6-Methoxy-2-naphthyl)propanoic acid
  • See more synonyms
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