CAS 22204-88-2

Tramadol hydrochloride

Description:

Tramadol hydrochloride is a synthetic opioid analgesic primarily used to manage moderate to moderately severe pain. It functions by binding to the mu-opioid receptors in the brain, inhibiting the reuptake of neurotransmitters such as serotonin and norepinephrine, which contributes to its analgesic effects. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various pharmaceutical formulations, including oral tablets and injectable solutions. Tramadol hydrochloride has a relatively low potential for abuse compared to other opioids, but it can still lead to dependence and withdrawal symptoms if misused. Common side effects include dizziness, nausea, constipation, and headache. Due to its effects on the central nervous system, caution is advised when prescribing tramadol, especially in patients with a history of substance use disorders or those taking other medications that may interact with it. Overall, tramadol hydrochloride is an important medication in pain management, but it requires careful monitoring and responsible use.

Formula: C₁₆H₂₅NO₂·ClH

InChI: InChI=1/C16H25NO2.ClH/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3;/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3;1H/t14-,16+;/s2

InChI key: InChIKey=PPKXEPBICJTCRU-NDFJEYLFNA-N

SMILES: O[C@]1([C@@H](CN(C)C)CCCC1)C2=CC(OC)=CC=C2.Cl

Synonyms:

• (-)-Tramadol hydrochloride
• (±)-trans-2-[(Dimethylamino)methyl]-1-(m-methoxyphenyl)cyclohexanol hydrochloride
• 2-[(Dimethylamino)Methyl]-1-(3-Methoxyphenyl)Cyclohexanol
• Abidol
• Adamon
• Adolonta
• Allapian
• Amadol
• Bellatram
• Cemadol
• Cg 315
• Contramal
• Crispin
• Cyclohexanol, 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-, hydrochloride (1:1), (1R,2R)-rel-
• Cyclohexanol, 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-, hydrochloride, (1R,2R)-rel-
• Cyclohexanol, 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-, hydrochloride, cis-
• Dolana
• Dolotram
• Ira-Tramadol
• Mabron
• Melanate
• Nih 10969
• Omnidol
• Poltram
• Radol
• Tadol
• Tedamol
• Topalgic
• Trabar
• Tradol
• Tradol-Puren
• Tradonal
• Tramadex
• Tramadol-Pharma
• Tramagetic
• Tramagit
• Tramal
• Tramal Retard
• Tramazac
• Tramed
• Tramol
• Tramundin
• Tridol
• Tridural
• Trodon
• Ultram
• Ultram Er
• Viotra
• Zumatran
• Zydol
• Zydol XL 150

cis-Tramadol HCl

Controlled Product

CAS: 22204-88-2

Tramadol is a non-narcotic analgesic that is used to treat severe and chronic pain. It binds to the mu-opioid receptors in the brain, which reduces the perception of pain. Tramadol is a prodrug that is metabolized into active metabolites by liver enzymes. The inactive form of tramadol, which has no therapeutic effect, is called cis-tramadol. Tramadol can be taken orally or intravenously, but its bioavailability is low due to extensive first-pass metabolism in the liver. Cis-Tramadol HCl has been shown to have an excellent analgesic effect in animal tests. This drug also has a kinetic profile suitable for use as an anti-inflammatory agent.

Formula: C₁₆H₂₆ClNO₂

Purity: Min. 95%

Molecular weight: 299.84 g/mol

Ref: 3D-FT165304