CAS 2222354-29-0

SNIPER(ABL)-039

CAS: 2222354-29-0

SNIPER(ABL)-039, conjugating Dasatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of

Formula: C₅₄H₆₈ClN₁₁O₉S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 1114.77

Ref: TM-T18690

SNIPER(ABL)-039

CAS: 2222354-29-0

SNIPER(ABL)-039 is a heterobifunctional chemical compound, which is a synthetic molecule manufactured through advanced organic synthesis techniques. This compound functions by specifically targeting and binding to aberrant BCR-ABL fusion proteins, utilizing a protein degradation pathway. It operates through the proteolysis-targeting chimera (PROTAC) mechanism, whereby it recruits E3 ubiquitin ligase to the target protein, leading to its ubiquitination and subsequent proteasomal degradation.

Formula: C₅₄H₆₈ClN₁₁O₉S₂

Purity: Min. 95%

Molecular weight: 1,114.8 g/mol

Ref: 3D-XND35429