CAS 22232-54-8

Carbimazole

Description:

Carbimazole is an antithyroid medication primarily used to treat hyperthyroidism, particularly in conditions such as Graves' disease. It functions by inhibiting the synthesis of thyroid hormones, thereby reducing their levels in the body. Chemically, carbimazole is classified as a thioamide and is a prodrug that is converted into its active form, methimazole, in the body. It has a molecular formula that includes carbon, hydrogen, nitrogen, and sulfur, reflecting its thioamide structure. Carbimazole is typically administered orally and is known for its relatively rapid onset of action. Common side effects may include gastrointestinal disturbances, skin rashes, and, in rare cases, agranulocytosis, a potentially serious decrease in white blood cell count. Monitoring of thyroid function and blood counts is essential during treatment. The substance is generally well-tolerated, but its use requires careful consideration of potential interactions with other medications and individual patient factors. As with any medication, it is important to follow a healthcare provider's guidance when using carbimazole.

Formula: C₇H₁₀N₂O₂S

InChI: InChI=1S/C7H10N2O2S/c1-3-11-7(10)9-5-4-8(2)6(9)12/h4-5H,3H2,1-2H3

InChI key: InChIKey=CFOYWRHIYXMDOT-UHFFFAOYSA-N

SMILES: C(OCC)(=O)N1C(=S)N(C)C=C1

Synonyms:

• 1-Ethoxycarbonyl-3-methyl-2-thio-4-imidazoline
• 1-Methyl-3-carbethoxy-2-thioglyoxalone
• 1H-Imidazole-1-carboxylic acid, 2,3-dihydro-3-methyl-2-thioxo-, ethyl ester
• 3-Carbethoxymercapto-1-methylimidazole
• 3-Carbethoxythio-1-methylglyoxaline
• 3-Carbethoxythio-1-methyliminazole
• 4-Imidazoline-1-carboxylic acid, 3-methyl-2-thioxo-, ethyl ester
• Athyromazole
• Basolest
• Carbethoxymethimazole
• Carbimazol
• Cg 1
• Ethyl 3-methyl-2-thioimidazoline-1-carboxylate
• Ethyl 3-methyl-2-thionoimidazoline-1-carboxylate
• Ethyl 3-methyl-2-thioxo-4-imidazoline-1-carboxylate
• Ethyl 3-methyl-2-thioxo-Δ4-imidazoline-1-carboxylate
• Ethyl 3-methyl-2-thioxo-Δ⁴-imidazoline-1-carboxylate
• Neo-Mercazole
• Neo-Thyreostat
• Neomercazole
• Tyrazol
• ethyl 3-methyl-2-thioxo-2,3-dihydro-1H-imidazole-1-carboxylate

Ethyl 3-methyl-2-thionoimidazoline-1-carboxylate, 97%

CAS: 22232-54-8

Ethyl 3-methyl-2-thionoimidazoline-1-carboxylate is used as thyroid inhibitor. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code o

Formula: C₇H₁₀N₂O₂S

Purity: 97%

Color and Shape: Crystals or powder or crystalline powder or fused solid, White

Molecular weight: 186.23

Ref: 02-L08218

Carbimazole

CAS: 22232-54-8

Color and Shape: Neat

Ref: 61-FOR1748.00

CARBIMAZOLE CRS

CAS: 22232-54-8

CARBIMAZOLE CRS

Ref: 41-C0465000

Carbimazole

CAS: 22232-54-8

Carbimazole

Formula: C₇H₁₀N₂O₂S

Purity: 99.9%

Color and Shape: White To Light Beige

Molecular weight: 186.0463

Ref: 47-749

Carbimazole

CAS: 22232-54-8

Carbimazole, an imidazolium-based thyroid blocker, turns to MMI in the body. Used in Graves' disease research.

Formula: C₇H₁₀N₂O₂S

Purity: 99.98%

Color and Shape: Solid

Molecular weight: 186.23

Ref: TM-T0952

Carbimazole

CAS: 22232-54-8

Formula: C₇H₁₀N₂O₂S

Purity: 97%

Color and Shape: Solid

Molecular weight: 186.2315

Ref: IN-DA003OP9

Carbimazole, BP, Ph. Eur. grade

CAS: 22232-54-8

Formula: C₇H₁₀N₂O₂S

Purity: ≤ 0.1%

Color and Shape: White or pale yellow crystalline powder

Molecular weight: 186.24

Ref: 7W-GP3531

Carbimazole

CAS: 22232-54-8

Carbimazole

Purity: ≥98%

Molecular weight: 186.23g/mol

Ref: 54-BUP18412

Carbimazole

CAS: 22232-54-8

Carbimazole

Purity: 97%

Molecular weight: 186.23g/mol

Ref: 54-OR1030132

Carbimazole

CAS: 22232-54-8

Formula: C₇H₁₀N₂O₂S

Purity: ≥ 98.0%

Color and Shape: White to almost white powder or crystals

Molecular weight: 186.24

Ref: 7W-GP8410

Carbimazole

CAS: 22232-54-8

Formula: C₇H₁₀N₂O₂S

Molecular weight: 186.23

Ref: 4Z-C-175002

Carbimazole

CAS: 22232-54-8

Formula: C₇H₁₀N₂O₂S

Color and Shape: Neat

Molecular weight: 186.23

Ref: 86-MM1748.00

Carbimazole

CAS: 22232-54-8

Applications Carbimazole, a prodrug of Methimazole (M260300), is used in the treatment of hyperthyroidism.
References Marchant, B., et al.: J. Clin. Endocrinol. Metab., 45, 1187 (1977), Johnsson, E., et al.: Lancet, 350, 1520 (1997),

Formula: C₇H₁₀N₂O₂S

Color and Shape: Neat

Molecular weight: 186.23

Ref: TR-C175960

Carbimazole - Bio-X ™

CAS: 22232-54-8

Carbimazole is an imidazole antithyroid agent that is used to treat hyperthyroidism. It reduces the production of diiodotyrosine and thyroxine, as well as the uptake and concentration of inorganic iodine by the thyroid. Once it has been converted to methimazole, the thyroid peroxidase enzyme is inhibited from coupling and iodinating the tyrosine residues on thyroglobulin therefore lowering the production of the thyroid hormones T3 and T4.

Formula: C₇H₁₀N₂O₂S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 186.23 g/mol

Ref: 3D-BE164282

Carbimazole

CAS: 22232-54-8

Inhibitor of thyroperoxidase; treats hypethyroidism

Formula: C₇H₁₀N₂O₂S

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 186.23 g/mol

Ref: 3D-FE19698

Carbimazole

CAS: 22232-54-8

Formula: C₇H₁₀N₂O₂S

Purity: >95.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 186.23

Ref: 3B-C1080

Carbimazole

CAS: 22232-54-8

Formula: C₇H₁₀N₂O₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 186.23

Ref: 10-F053981

Carbimazole-d3

Controlled Product

CAS: 22232-54-8

Formula: C₇D₃H₇N₂O₂S

Color and Shape: Neat

Molecular weight: 189.25

Ref: TR-C175962