CAS 22232-71-9

Mazindol

Description:

Mazindol is a pharmaceutical compound primarily recognized for its use as an appetite suppressant in the treatment of obesity. It belongs to the class of compounds known as central nervous system stimulants. Chemically, mazindol is characterized by its structure, which includes a phenyl ring and a piperidine moiety, contributing to its pharmacological activity. The substance acts by inhibiting the reuptake of neurotransmitters such as norepinephrine and dopamine, thereby promoting increased energy expenditure and reduced appetite. Mazindol is typically administered orally and has a relatively long half-life, allowing for once-daily dosing in clinical settings. While it has shown efficacy in weight management, its use is often limited due to potential side effects, including insomnia, dry mouth, and increased heart rate. Additionally, mazindol is classified as a controlled substance in some regions due to its stimulant properties, necessitating careful monitoring and regulation in its prescription and use. Overall, mazindol represents a unique option in the pharmacotherapy of obesity, albeit with considerations for safety and efficacy.

Formula: C₁₆H₁₃ClN₂O

InChI: InChI=1/C16H13ClN2O/c17-12-7-5-11(6-8-12)16(20)14-4-2-1-3-13(14)15-18-9-10-19(15)16/h1-8,20H,9-10H2

InChI key: InChIKey=ZPXSCAKFGYXMGA-UHFFFAOYSA-N

SMILES: OC1(N2C(C=3C1=CC=CC3)=NCC2)C4=CC=C(Cl)C=C4

Synonyms:

• 3H-Imidazo[2,1-a]isoindol-5-ol, 5-(p-chlorophenyl)-2,5-dihydro-
• 5-(4-Chlorophenyl)-2,3-dihydro-5-hydroxy-5H-imidazo[2,1-a]isoindole
• 5-(4-Chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol
• 5-(p-Chlorophenyl)-2,3-dihydro-5H-imidazo[2,1-a]isoindol-5-ol
• 5-(p-Chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol
• 5-(p-Chlorophenyl)-5-hydroxy-2,3-dihydro-5H-imidazo[2,1-a]isoindole
• 5-Hydroxy-5-p-chlorophenyl-2,3-dihydro-5H-imidazo[2,1-a]isoindole
• An 448
• Magrilon
• Mazanor
• Mazildene
• Mazindol
• SaH 42548
• Sanorex
• Terenac
• Teronac
• 3H-Imidazo[2,1-a]isoindol-5-ol, 5-(4-chlorophenyl)-2,5-dihydro-
• MAZINDOOL
• 5H-Imidazo(2,1-a)isoindol-5-ol, 5-(4-chlorophenyl)-2,3-dihydro-
• 1-a)isoindol-5-ol,2,5-dihydro-5-(4-chlorophenyl)-3h-imidazo(
• 1-a]isoindol-5-ol,5-(4-chlorophenyl)-2,5-dihydro-3h-imidazo[
• MAZINDOLE
• dimagrir
• 1-a)isoindol-5-ol,5-(4-chlorophenyl)-2,5-dihydro-3h-imidazo(
• 5h-imidazo(2,1-a)isoindol-5-ol,5-(4-chlorophenyl)-2,3-dihydro
• 1-a)isoindol-5-ol,5-(p-chlorophenyl)-2,5-dihydro-3h-imidazo(

Mazindol

Controlled Product

CAS: 22232-71-9

Color and Shape: Neat

Ref: LP-MZD-1274-FB-10

Mazindol, 1mg/ml in Dmf

Controlled Product

CAS: 22232-71-9

Color and Shape: Single Solution

Ref: LP-MZD-1274-FB-1LD

Mazindol

Controlled Product

CAS: 22232-71-9

Applications Clinical trials as appetite depressant. Anorexic; CNS stimulant. Controlled substance (stimulant).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sirtori, C., et al.: Am. J. Med. Sci., 261, 341 (1971), Hadler, A.J., et al.: J. Clin. Pharmacol., 12, 453 (1972), Thompson, D.A., et al.: Metabolism., 30, 1015 (1981),

Formula: C₁₆H₁₃ClN₂O

Color and Shape: Off-White

Molecular weight: 284.74

Ref: TR-M198500

Mazindol

Controlled Product

CAS: 22232-71-9

Inhibitor of dopamine uptake carrier

Formula: C₁₆H₁₃ClN₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 284.74 g/mol

Ref: 3D-FM156784