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CAS 222400-20-6

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Tomopenem

Description:
Tomopenem is a synthetic carbapenem antibiotic that exhibits broad-spectrum antibacterial activity, particularly against Gram-positive and Gram-negative bacteria. It is characterized by its β-lactam structure, which is essential for its mechanism of action, as it inhibits bacterial cell wall synthesis. Tomopenem is notable for its stability against various β-lactamases, enzymes produced by bacteria that confer resistance to many antibiotics. This stability enhances its efficacy against resistant strains. The compound is typically administered parenterally and is used in the treatment of serious infections, including those caused by multidrug-resistant organisms. Its pharmacokinetic properties include good tissue penetration and a relatively short half-life, necessitating multiple doses for effective therapeutic levels. Additionally, Tomopenem's safety profile is generally favorable, although, like other antibiotics, it may be associated with potential side effects such as gastrointestinal disturbances or allergic reactions. Ongoing research continues to evaluate its effectiveness and safety in various clinical settings.
Formula:C23H35N7O6S
InChI:InChI=1S/C23H35N7O6S/c1-10-17-16(11(2)31)21(34)30(17)18(22(35)36)19(10)37-13-6-14(28(3)9-13)20(33)29-5-4-12(8-29)27-15(32)7-26-23(24)25/h10-14,16-17,31H,4-9H2,1-3H3,(H,27,32)(H,35,36)(H4,24,25,26)/t10-,11-,12+,13+,14+,16-,17-/m1/s1
InChI key:InChIKey=KEDAXBWZURNCHS-GPODMPQUSA-N
SMILES:C(O)(=O)C=1N2[C@@]([C@@]([C@@H](C)O)(C2=O)[H])([C@@H](C)C1S[C@H]3C[C@@H](C(=O)N4C[C@@H](NC(CNC(=N)N)=O)CC4)N(C)C3)[H]
Synonyms:
  • (4R,5S,6S)-3-[[(3S,5S)-5-[[(3S)-3-[[2-[(Aminoiminomethyl)amino]acetyl]amino]-1-pyrrolidinyl]carbonyl]-1-methyl-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[[(3S)-3-[[2-[(aminoiminomethyl)amino]acetyl]amino]-1-pyrrolidinyl]carbonyl]-1-methyl-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, (4R,5S,6S)-
  • 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[[(3S)-3-[[[(aminoiminomethyl)amino]acetyl]amino]-1-pyrrolidinyl]carbonyl]-1-methyl-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, (4R,5S,6S)-
  • Antibiotic CS 023
  • Cs-023
  • R 1558
  • R-115685
  • R-1558，Ro-4098463
  • Ro 4908463
  • Tomopenem
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Found 3 products.
  • Tomopenem
    Targetmol
    + Info

    Tomopenem

    CAS:
    <p>Tomopenem is a penem antibiotic.</p>
    Formula:C23H35N7O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:537.63

    Ref: TM-T28992

  • Tomopenem
    Biosynth
    + Info

    Tomopenem

    CAS:
    <p>Tomopenem is a carbapenem antibiotic, which is a product of synthetic origin with broad-spectrum antibacterial properties. It acts by inhibiting the synthesis of bacterial cell walls through binding to penicillin-binding proteins, thereby disrupting the structural integrity of the cell wall and leading to bacterial cell lysis and death.</p>
    Formula:C23H35N7O6S
    Purity:Min. 95%
    Molecular weight:537.63 g/mol

    Ref: 3D-AT28326

    ne
    To inquire
  • Tomopenem
    TRC
    + Info

    Tomopenem

    Controlled Product
    CAS:
    <p>Applications Carbapenem Antibiotic.<br>References Shahid, M., et al.: Crit. Rev. Microbiol., 35, 81 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009), Mallalieu, N., et al.: Brit. J. Clin. Pharmacol., 67, 469 (2009),<br></p>
    Formula:C23H35N7O6S
    Color and Shape:Neat
    Molecular weight:537.632

    Ref: TR-T538550

    50mg
    28,963.00€