CAS 22252-43-3
:7-Aminodeacetoxycephalosporanic acid
Description:
7-Aminodeacetoxycephalosporanic acid (CAS 22252-43-3) is a crucial intermediate in the synthesis of cephalosporin antibiotics, which are widely used to treat bacterial infections. This compound features a beta-lactam ring, characteristic of cephalosporins, which is essential for its antibacterial activity. It possesses an amino group at the 7-position, contributing to its reactivity and ability to undergo further chemical modifications to produce various cephalosporin derivatives. The structure also includes a deacetoxy group, which differentiates it from other cephalosporins. 7-Aminodeacetoxycephalosporanic acid is typically a white to off-white crystalline powder, soluble in water and organic solvents, making it suitable for pharmaceutical applications. Its stability and reactivity are influenced by pH and temperature, which are critical factors to consider during storage and handling. This compound serves as a key building block in the development of semi-synthetic antibiotics, highlighting its importance in medicinal chemistry and the pharmaceutical industry.
Formula:C8H10N2O3S
InChI:InChI=1S/C8H10N2O3S/c1-3-2-14-7-4(9)6(11)10(7)5(3)8(12)13/h4,7H,2,9H2,1H3,(H,12,13)/t4-,7-/m1/s1
InChI key:InChIKey=NVIAYEIXYQCDAN-CLZZGJSISA-N
SMILES:C(O)(=O)C=1N2[C@@]([C@H](N)C2=O)(SCC1C)[H]
Synonyms:- (6R,7R)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- (6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- (6S,7S)-7-ammonio-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- 3-Methyl-7-amino-Δ<sup>3</sup>-cephem-4-carboxylic acid
- 3-Methyl-7-aminoceph-3-em-4-carboxylic acid
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-methyl-8-oxo-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-methyl-8-oxo-, (6R,7R)-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-methyl-8-oxo-, (6R-trans)-
- 7-Adca
- 7-Amino-3-deacetoxycephalosporanic acid
- 7-Amino-3-desacetoxycephalosporanic acid
- 7-Amino-3-methyl-3-cephen-4-carboxylic acid
- 7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
- 7-Amino-3-methyl-Δ<sup>3</sup>-cephan-4-carboxylic acid
- 7-Amino-3-methyl-Δ<sup>3</sup>-cephem-4-carboxylic acid
- 7-Amino-3-methylcephalosporanic acid
- 7-Aminodeacetoxycephalexanic acid
- 7-Aminodeacetoxycephalosporanic acid
- 7-Aminodeacetoxycephalosporanic ccid
- 7-Aminodesacetoxycephalosporanic acid
- 7-β-Amino-3-methyl-3-cephem-4-carboxylic acid
- 7β-Amino-3-methylceph-3-em-4-carboxylic acid
- Deacetoxycephalosporanic acid
- See more synonyms
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Found 16 products.
Cefadroxil Related Compound B ((6R,7R)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C8H10N2O3SColor and Shape:Off-White Crystalline PowderMolecular weight:214.041217-Aminodeacetoxycephalosporanic acid
CAS:<p>7-Aminodeacetoxycephalosporanic acid (Cefalexine EP IMpurity B) is used as an antibiotic.</p>Formula:C8H10N2O3SPurity:98.87% - 99.63%Color and Shape:White Solid PowderMolecular weight:214.24(6R,7S)-7-AMINO-3-METHYL-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID
CAS:Formula:C8H10N2O3SPurity:97%Color and Shape:SolidMolecular weight:214.2416Cefadroxil EP Impurity B (Cefadroxil USP Related Compound B, Cephalexin (Cephalexin) EP Impurity B, Cefradine EP Impurity A, 7-ADCA)
CAS:Formula:C8H10N2O3SColor and Shape:White To Off-White SolidMolecular weight:214.247-Aminodesacetoxycephalosporanic Acid
CAS:7-Aminodesacetoxycephalosporanic AcidPurity:98%Molecular weight:214.24g/mol7-Aminodeacetoxycephalosporanic acid
CAS:7-Aminodeacetoxycephalosporanic acidPurity:≥98%Molecular weight:214.24g/mol7-Aminodesacetoxycephalosporanic Acid
CAS:Controlled ProductFormula:C8H10N2O3SColor and Shape:NeatMolecular weight:214.247-Aminodesacetoxycephalosporanic Acid
CAS:Formula:C8H10N2O3SPurity:>98.0%(HPLC)Color and Shape:White to Orange to Green powder to crystallineMolecular weight:214.247-Aminodesacetoxycephalosporanic acid
CAS:Formula:C8H10N2O3SPurity:≥ 98.0%Color and Shape:White to off-white or pale yellow powderMolecular weight:214.247-Aminodesacetoxycephalosporanic Acid
CAS:<p>Impurity Cefadroxil EP Impurity B<br>Applications 7-Aminodesacetoxycephalosporanic Acid (Cefadroxil EP Impurity B) is a metabolite of Cephalexin (C256800).<br>References Dantzig, A., et al.: Biochim. Biophys. Acta, 1027, 211 (1990), Shen, H., et al.: J. Biol. Chem., 278, 4786 (2003), Watanabe, C., et al.: Drug Metab. Pharmacokinet., 20, 443 (2005)<br></p>Formula:C8H10N2O3SColor and Shape:BeigeMolecular weight:214.247-Aminodezacetoxycephalosporanic acid
CAS:Purity:98.0%Color and Shape:Solid, PowderMolecular weight:214.240005493164067-Aminodesacetoxycephalosporanic acid
CAS:<p>7-Aminodesacetoxycephalosporanic acid is a chemical compound that is used for wastewater treatment as a biocatalyst. It has been shown to have group P2 activity and can be used in the treatment of corynebacterium glutamicum. 7-Adca has been found to bind to the magnesium salt, which leads to control analysis and kinetic studies. The reactions are initiated by the addition of an electron donor, such as penicillin, which results in a transfer reaction. The nitrogen atoms are substituted with hydrogen atoms, which produces a fatty acid intermediate. This intermediate reacts with nitrogen atoms from another molecule of 7-Adca or 7-adca to form an amide bond. The amide bond is then hydrolyzed in water to produce 7-aminodesacetoxycephalosporanic acid and ammonia.</p>Formula:C8H10N2O3SPurity:Min. 95%Color and Shape:White PowderMolecular weight:214.24 g/mol
![(6R,7S)-7-AMINO-3-METHYL-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA003NCS.jpg&w=3840&q=75)
