CAS 22254-24-6: Ipratropium bromide
Description:Ipratropium bromide is a synthetic quaternary ammonium compound primarily used as a bronchodilator in the treatment of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). It functions as an anticholinergic agent, inhibiting the action of acetylcholine on muscarinic receptors in the airways, leading to relaxation of bronchial smooth muscle and improved airflow. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for inhalation formulations. Its chemical formula is C20H30BrN2O3, and it has a molecular weight of approximately 392.37 g/mol. Ipratropium bromide is typically administered via inhalation, either through metered-dose inhalers or nebulizers, allowing for localized action in the lungs with minimal systemic side effects. Common side effects may include dry mouth, cough, and throat irritation. Due to its mechanism of action, it is often used in combination with beta-agonists to enhance therapeutic efficacy in managing bronchospasm.
Formula:C20H30NO3·Br
InChI:InChI=1/C20H30NO3.BrH/c1-14(2)21(3)16-9-10-17(21)12-18(11-16)24-20(23)19(13-22)15-7-5-4-6-8-15;/h4-8,14,16-19,22H,9-13H2,1-3H3;1H/q+1;/p-1/t16-,17+,18+,19?,21+;
InChI key:InChIKey=LHLMOSXCXGLMMN-VVQPYUEFNA-M
SMILES:[Br-].O=C(OC1CC2CCC(C1)[N+]2(C)C(C)C)C(C=3C=CC=CC3)CO
- Synonyms:
- (1R,5S)-3-[(3-hydroxy-2-phenylpropanoyl)oxy]-8-methyl-8-(propan-2-yl)-8-azoniabicyclo[3.2.1]octane bromide
- 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropanium, 3α-hydroxy-8-isopropyl-, bromide, (±)-tropate
- 3-[(3-Hydroxy-2-Phenylpropanoyl)Oxy]-8-Methyl-8-(Propan-2-Yl)-8-Azoniabicyclo[3.2.1]Octane Bromide
- 8-Azoniabicyclo[3.2.1]octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-, bromide (1:1), (3-endo,8-syn)-
- 8-Azoniabicyclo[3.2.1]octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-, bromide, (3-endo,8-syn)-
- 8-Azoniabicyclo[3.2.1]octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-, bromide, (endo,syn)-
- 8-Isopropylatropinium bromide
- Aerovent
- Atrovent
- Atrovent forte
- See more synonyms
- IpratropiumBromide
- Ipraxa
- N-Isopropylatropinium bromide
- N-Isopropylnoratropinium bromomethylate
- Sch 100
- Sch 1000
- [(1R)-8-isopropyl-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenyl-propanoate bromide
- 1αH,5αH-Tropanium, 3α-hydroxy-8-isopropyl-, bromide, (±)-tropate
