CAS 22254-24-6

Ipratropium bromide

Description:

Ipratropium bromide is a synthetic quaternary ammonium compound primarily used as a bronchodilator in the treatment of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). It functions as an anticholinergic agent, inhibiting the action of acetylcholine on muscarinic receptors in the airways, leading to relaxation of bronchial smooth muscle and improved airflow. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for inhalation formulations. Its chemical formula is C20H30BrN2O3, and it has a molecular weight of approximately 392.37 g/mol. Ipratropium bromide is typically administered via inhalation, either through metered-dose inhalers or nebulizers, allowing for localized action in the lungs with minimal systemic side effects. Common side effects may include dry mouth, cough, and throat irritation. Due to its mechanism of action, it is often used in combination with beta-agonists to enhance therapeutic efficacy in managing bronchospasm.

Formula: C₂₀H₂₉Br₂NO₃

InChI: InChI=1/C20H30NO3.BrH/c1-14(2)21(3)16-9-10-17(21)12-18(11-16)24-20(23)19(13-22)15-7-5-4-6-8-15;/h4-8,14,16-19,22H,9-13H2,1-3H3;1H/q+1;/p-1/t16-,17?,18-,19?,21?;/m1./s1

InChI key: InChIKey=LHLMOSXCXGLMMN-VVQPYUEFNA-M

SMILES: C(C)(C)[N@@+]1(C)[C@]2(C[C@H](OC(C(CO)C3=CC=CC=C3)=O)C[C@@]1(CC2)[H])[H].[Br-]

Synonyms:

• (1R,5S)-3-[(3-hydroxy-2-phenylpropanoyl)oxy]-8-methyl-8-(propan-2-yl)-8-azoniabicyclo[3.2.1]octane bromide
• 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropanium, 3α-hydroxy-8-isopropyl-, bromide, (±)-tropate
• 3-[(3-Hydroxy-2-Phenylpropanoyl)Oxy]-8-Methyl-8-(Propan-2-Yl)-8-Azoniabicyclo[3.2.1]Octane Bromide
• 8-Azoniabicyclo[3.2.1]octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-, bromide (1:1), (3-endo,8-syn)-
• 8-Azoniabicyclo[3.2.1]octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-, bromide, (3-endo,8-syn)-
• 8-Azoniabicyclo[3.2.1]octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-, bromide, (endo,syn)-
• 8-Isopropylatropinium bromide
• Aerovent
• Atrovent
• Atrovent forte
• IpratropiumBromide
• Ipraxa
• N-Isopropylatropinium bromide
• N-Isopropylnoratropinium bromomethylate
• Sch 100
• Sch 1000
• [(1R)-8-isopropyl-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenyl-propanoate bromide
• 1αH,5αH-Tropanium, 3α-hydroxy-8-isopropyl-, bromide, (±)-tropate
• ipratropiumbromid
• (ENDO,SYN)-(+/-)-3-(3-HYDROXY-1-OXO-2-PHENYLPROPOXY)-8-METHYL-8-(1-METHYLETHYL)-8-AZONIABICYCLO[3.2.1]OCTANE BROMIDE
• pate
• (3-endo,8-syn)-3-(3-Hydroxy-1-oxo-2-phenylpropyl)-8-methyl-8-(1-methylethyl)-8-azoniabicyclo[3.2.1]octane Bromode Monohydrate
• IPRATROPIUM BROMIDE MONOHYDRATE
• 1-alpha-h,5-alpha-h-tropanium,3-alpha-hydroxy-8-isopropyl-,bromide,(+-)-trop
• atem
• Atropine Isopropyl Bromid
• 8-isopropylnoratropinemethobromide
• itrop
• IPRATROPIUM BROMIDE HYDRATE
• [(1r,5s)-8-methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate bromide
• (1s,3s,5r)-3-tropyloxy-8-isopropyltropaniumbromide
• n-isopropylnoratropiniumbromomethylate
• ATROPINE ISOPROPYLBROMIDE
• 3-alpha-hydroxy-8-isopropyl-1-alpha-h,5-alpha-h-tropaniumbromide(+-)-tropat
• 3-(3-HYDROXY-1-OXO-2-PHENYLPROPOXY)-8-METHYL-8-(1-METHYLETHYL)-8-AZONIABICYCLO[3.2.1]-OCTANE BROMIDE
• sch1000

Ipratropium bromide, 98%

CAS: 22254-24-6

Muscarinic acetylcholine receptor antagonist and a bronchodilator

Formula: C₂₀H₃₀BrNO₃

Purity: 98%

Color and Shape: White to cream, Powder

Molecular weight: 412.37

Ref: 02-J60453

Ipratropium-d3 Bromide

CAS: 22254-24-6

Formula: C₂₀H₂₇D₃NO₃·Br

Color and Shape: White To Off-White Solid

Molecular weight: 335.48 79.90

Ref: 4Z-I-111

Ipratropium Bromide

CAS: 22254-24-6

Ipratropium Bromide

Purity: ≥98%

Molecular weight: 412.37g/mol

Ref: 54-BUP16104

Ipratropium-d3 Bromide(N-methyl-d3) marquée 22254-24-6

CAS: 22254-24-6

Purity: 99 atom % D

Color and Shape: White Solid

Molecular weight: 415.38

Ref: 3U-D6923

Ipratropium Bromide Monohydrate

CAS: 22254-24-6, 60205-81-4, 66985-17-9

Formula: C₂₀H₃₀BrNO₃·H₂O

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 430.39

Ref: 3B-I0907

Ipratropium Bromide

CAS: 22254-24-6

Ipratropium Bromide (Sch 1000) is an antagonist of muscarinic receptors and is used in COPD and asthma studies.

Formula: C₂₀H₃₀BrNO₃

Purity: 99.92%

Color and Shape: Solid

Molecular weight: 412.37

Ref: TM-T6547

Ipratropium Bromide

Controlled Product

CAS: 22254-24-6

Applications Ipratropium Bromide is a nonselective muscarinic acetylcholine receptor antagonist; bronchodilator.
References Groeben, H., et al.: Anesthesiology, 85, 867 (1996); Haddad, et al.: Br. J. Pharmacol., 127, 413 (1999); Barnes, P. J., et al.: Chest, 117, 63S (2000)

Formula: C₂₀H₃₀NO₃·Br

Color and Shape: White

Molecular weight: 412.36

Ref: TR-I740495

Ipratropium-d7 Bromide

Controlled Product

CAS: 22254-24-6

Applications N-Isopropyl quaternary salt of Atropine. Nonselective muscarinic acetylcholine receptor antagonist; bronchodilator.
References Groeben, H., et al.: Anesthesiology, 85, 867 (1996), Haddad, et al.: Br. J. Pharmacol., 127, 413 (1999), Barnes, P. J., et al.: Chest, 117, 63S (2000),

Formula: C₂₀H₂₃D₇BrNO₃

Color and Shape: Neat

Molecular weight: 419.4

Ref: TR-I740503

Ipratropium bromide

CAS: 22254-24-6

Muscarinic antagonist

Formula: C₂₀H₃₀BrNO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 412.36 g/mol

Ref: 3D-FI44992

Ipratropium bromide - Bio-X ™

CAS: 22254-24-6

Ipratropium is an ammonium derivative of atropine and acts as an anticholinergic drug that is used for the control of bronchospasms in chronic obstructive pulmonary disease (COPD). This drug is an antagonist of muscarinic acetylcholine receptors and produces an inhibitor of the parasympathetic system. As a result, this leads to bronchodilation and fewer bronchial secretions.

Formula: C₂₀H₃₀BrNO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 412.36 g/mol

Ref: 3D-BI164579

(±)-Ipratropium-d3 Bromide (N-methyl-d3)

Controlled Product

CAS: 22254-24-6

Formula: C₂₀D₃H₂₇NO₃·Br

Color and Shape: Neat

Molecular weight: 415.38

Ref: TR-I740501