CAS 22258-56-6
:4-(1H-indol-3-yl)-1,3-thiazol-2-amine
Description:
4-(1H-indol-3-yl)-1,3-thiazol-2-amine, with the CAS number 22258-56-6, is a chemical compound characterized by its unique structural features, which include an indole moiety and a thiazole ring. This compound typically exhibits properties associated with both aromatic and heterocyclic compounds, contributing to its potential biological activity. The presence of the indole structure suggests possible interactions with biological systems, as indoles are known for their roles in various pharmacological activities. The thiazole ring adds to the compound's reactivity and may influence its solubility and stability. In terms of physical properties, compounds of this nature often display moderate to high melting points and can be soluble in organic solvents. Additionally, 4-(1H-indol-3-yl)-1,3-thiazol-2-amine may possess potential applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting various diseases, owing to the biological significance of both indole and thiazole derivatives. Further studies would be necessary to fully elucidate its properties and potential uses.
Formula:C11H9N3S
InChI:InChI=1/C11H9N3S/c12-11-14-10(6-15-11)8-5-13-9-4-2-1-3-7(8)9/h1-6,13H,(H2,12,14)
SMILES:c1ccc2c(c1)c(c[nH]2)c1csc(=N)[nH]1
Synonyms:- 2-Thiazolamine, 4-(1H-indol-3-yl)-
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Found 2 products.
4-(1H-Indol-3-yl)-thiazol-2-ylamine
CAS:4-(1H-Indol-3-yl)-thiazol-2-ylamine is a novel small molecule that has been shown to have anti-cancer activity. This drug induces apoptosis by activation of the caspase-3 pathway and minimal toxicity in human cells. 4-(1H-Indol-3-yl)-thiazol-2-ylamine has also been shown to be effective against cancer cells that are resistant to chemotherapeutic drugs. The drug's ability to inhibit cell proliferation may be due to its ability to activate p53, which is a cellular protein that regulates cell growth and death. 4-(1H-Indol-3-yl)-thiazol-2-ylamine activates caspase 3 in MDA MB231 breast cancer cells, leading to apoptosis or programmed cell death.
Formula:C11H9N3SPurity:Min. 95%Molecular weight:215.28 g/mol

