CymitQuimica logo

CAS 2225940-52-1

:

E3 Ligase Ligand-Linker Conjugates 22

Description:
E3 Ligase Ligand-Linker Conjugates, specifically the compound identified by the CAS number 2225940-52-1, are specialized chemical entities designed for targeted protein degradation through the ubiquitin-proteasome system. These conjugates typically consist of a ligand that binds to an E3 ubiquitin ligase, a linker that connects the ligand to a target protein, and a moiety that interacts with the target protein itself. The primary characteristic of these compounds is their ability to facilitate the ubiquitination of specific proteins, leading to their subsequent degradation. This mechanism is of significant interest in drug discovery and development, particularly for the treatment of diseases such as cancer, where the degradation of oncogenic proteins can restore normal cellular function. The design of these conjugates often involves careful consideration of the linker length and composition to ensure optimal binding and activity. Additionally, their stability, solubility, and bioavailability are critical factors that influence their efficacy in biological systems. Overall, E3 Ligase Ligand-Linker Conjugates represent a promising approach in the field of targeted therapeutics.
Formula:C23H32N4O8
Synonyms:
  • E3 Ligase Ligand-Linker Conjugates 22
  • Pomalidomide-PEG4-C2-NH2
  • 4-((14-amino-3,6,9,12-tetraoxatetradecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
  • 1H-Isoindole-1,3(2H)-dione, 4-[(14-amino-3,6,9,12-tetraoxatetradec-1-yl)amino]-2-(2,6-dioxo-3-piperidinyl)-
  • Cereblon Ligand-Linker Conjugates 8
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 4 products.