CAS 2226-72-4

[[(2S,3S,4R,5R)-5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]amino] dihydrogen phosphate

Description:

The chemical substance with the name "[[(2S,3S,4R,5R)-5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]amino] dihydrogen phosphate" and CAS number 2226-72-4 is a nucleotide analog that plays a significant role in biochemical processes. It features a tetrahydrofuran ring, which is a five-membered cyclic ether, and incorporates both amino and hydroxyl functional groups, contributing to its reactivity and interaction with biological molecules. The presence of a pyrimidine moiety suggests potential involvement in nucleic acid metabolism or as a substrate for enzymes in nucleotide synthesis. This compound is likely to exhibit polar characteristics due to its multiple hydroxyl and amino groups, enhancing its solubility in aqueous environments. Additionally, the dihydrogen phosphate group indicates that it can participate in phosphorylation reactions, which are crucial in cellular signaling and energy transfer. Overall, this compound's structural features suggest it may have applications in medicinal chemistry, particularly in the development of antiviral or anticancer agents.

Formula: C₈H₁₃N₄O₈P

InChI: InChI=1/C8H13N4O8P/c9-3-1-2-12(8(15)10-3)7-5(14)4(13)6(19-7)11-20-21(16,17)18/h1-2,4-7,11,13-14H,(H2,9,10,15)(H2,16,17,18)/t4-,5+,6-,7+/m0/s1

5-Azacytidine 5''-monophosphate

CAS: 2226-72-4

Ref: 7W-GN6618

5-Azacytidine 5'-monophosphate

CAS: 2226-72-4

Formula: C₈H₁₃N₄O₈P

Molecular weight: 324.19

Ref: 4Z-C-4528

5-Azacytidine 5'-monophosphate

CAS: 2226-72-4

5-Azacytidine 5'-monophosphate (5-Aza-CMP) is a modified nucleoside that inhibits DNA synthesis by competitively inhibiting the incorporation of deoxycytidine 5'-triphosphate into DNA. It is used as an antiviral and anticancer agent. 5-Aza-CMP has been shown to inhibit the proliferation of human cancer cells in vitro, including T cell leukemia, lymphoma, breast cancer, and melanoma.

Formula: C₈H₁₃N₄O₈P

Purity: Min. 95%

Color and Shape: White to off-white solid.

Molecular weight: 324.18 g/mol

Ref: 3D-NA09600

5-Azacytidine 5'-Monophosphate 60%

Controlled Product

CAS: 2226-72-4

Stability Hygroscopic
Applications A metabolite of 5-Azacytidine. This compound contains sodium chloride and water.
References Lee, T., et al.: Cancer Res., 34, 2482 ( (1974), Drake, J.C., et al.: Biochem. Pharmacol., 29, 807 (1980),

Formula: C₈H₁₃N₄O₈P

Purity: 60%

Color and Shape: Neat

Molecular weight: 324.18

Ref: TR-A796020

Azacitidine Monophosphate

CAS: 2226-72-4

Formula: C₈H₁₃N₄O₈P

Molecular weight: 324.19

Ref: ST-EA-CP-A35015