CAS 2226472-28-0
:DBCO-PEG4-Val-Cit-PAB-PNP
Description:
DBCO-PEG4-Val-Cit-PAB-PNP is a synthetic compound that belongs to the class of bioconjugates, often utilized in biochemistry and medicinal chemistry for targeted drug delivery and imaging applications. The structure features a dibenzocyclooctyne (DBCO) moiety, which is known for its efficient click chemistry properties, allowing for rapid and selective reactions with azides. The PEG4 (polyethylene glycol) segment enhances solubility and biocompatibility, making the compound suitable for biological applications. The Val-Cit (valine-citrulline) dipeptide serves as a cleavable linker, often used in prodrug designs to release active drugs in response to specific biological conditions. The PAB (p-aminobenzyl) group can facilitate further conjugation or serve as a protective group. The PNP (p-nitrophenyl) moiety is typically involved in the activation of the compound for subsequent reactions. Overall, DBCO-PEG4-Val-Cit-PAB-PNP is characterized by its multifunctionality, enabling it to serve as a versatile tool in the development of targeted therapies and diagnostic agents.
Formula:C55H66N8O15
Synonyms:- DBCO-PEG4-Val-Cit-PAB-PNP
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Found 3 products.
DBCO-PEG4-Val-Cit-PAB-PNP
CAS:<p>DBCO-PEG4-Val-Cit-PAB-PNP is a cleavable ADC linker where Val-Cit is specifically cleaved by Cathepsin B. The PNP group can be substituted by amine-containing payloads, and DBCO undergoes click chemistry reactions with azide molecules.</p>Formula:C55H66N8O15Color and Shape:SolidMolecular weight:1079.164-((17S,20S)-1-(DBCO-Butanedicarboxylamino)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosan-21-amido)benzyl (4-nitrophenyl) carbonate
CAS:4-((17S,20S)-1-(DBCO-Butanedicarboxylamino)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosan-21-amido)benzyl (4-nitrophenyl) carbonatePurity:98%Molecular weight:1079.17g/mol
