CAS 2227-64-7

3-Nitrophenacyl bromide

Description:

3-Nitrophenacyl bromide, with the CAS number 2227-64-7, is an organic compound characterized by its nitrophenyl and bromide functional groups. It typically appears as a yellow crystalline solid, indicating its aromatic nature and the presence of the nitro group, which contributes to its electrophilic reactivity. This compound is known for its role as a reagent in organic synthesis, particularly in the preparation of various derivatives and in photochemical reactions. The nitro group enhances the electrophilicity of the carbonyl carbon, making it a useful intermediate in the synthesis of more complex molecules. Additionally, 3-nitrophenacyl bromide can participate in nucleophilic substitution reactions, where the bromide can be replaced by various nucleophiles. Its reactivity and stability under certain conditions make it a valuable compound in chemical research and applications. However, as with many nitro compounds, it should be handled with care due to potential toxicity and environmental concerns.

Formula: C₈H₆BrNO₃

InChI: InChI=1S/C8H6BrNO3/c9-5-8(11)6-2-1-3-7(4-6)10(12)13/h1-4H,5H2

InChI key: InChIKey=GZHPNIQBPGUSSX-UHFFFAOYSA-N

SMILES: C(CBr)(=O)C1=CC(N(=O)=O)=CC=C1

Synonyms:

• 1-(3-Nitrophenyl)-2-bromoethanone
• 1-Nitro-3-(bromoacetyl)benzene
• 2-Bromo-1-(3-Nitrophenyl)Ethanone
• 2-Bromo-1-(3-nitrophenyl)ethan-1-one
• 2-Bromo-3'-nitroacetophenone
• 2-Bromo-m-nitroacetophenone
• 3-Nitro-2-Bromo Acetophenone
• 3-Nitrophenacyl bromide
• 3-Nitrophenacylbromide
• Acetophenone, 2-bromo-3′-nitro-
• Bromomethyl 3-nitrophenyl ketone
• Bromomethyl m-nitrophenyl ketone
• Ethanone, 2-bromo-1-(3-nitrophenyl)-
• NSC 69855
• m-Nitrophenacyl bromide
• Α-Bromo-3'-Nitroacetophenone
• α-Bromo-m-nitroacetophenone
• ω-Bromo-m-nitroacetophenone
• alpha-Bromo-3[-nitroacetophenone

Ethanone, 2-​bromo-​1-​(3-​nitrophenyl)​-

CAS: 2227-64-7

Formula: C₈H₆BrNO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 244.0421

Ref: IN-DA00BBLG

3''-Nitrophenacyl bromide

CAS: 2227-64-7

Formula: C₈H₆BrNO₃

Purity: ≥ 95.0%

Color and Shape: White to yellow powder or solid

Molecular weight: 244.05

Ref: 7W-GK3279

2-Bromo-3'-nitroacetophenone

CAS: 2227-64-7

Formula: C₈H₆BrNO₃

Purity: >97.0%(GC)(T)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 244.04

Ref: 3B-B2855

3-Nitrophenacyl bromide

CAS: 2227-64-7

3-Nitrophenacyl bromide

Formula: C₈H₆BrNO₃

Purity: 98%

Color and Shape: cream crystalline powder

Molecular weight: 244.04g/mol

Ref: 54-OR11094

3-Nitrophenacyl bromide

CAS: 2227-64-7

Formula: C₈H₆BrNO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 244.044

Ref: 10-F011206

a-Bromo-3'-nitroacetophenone

CAS: 2227-64-7

a-Bromo-3'-nitroacetophenone is a chemical compound that is used in the synthesis of other compounds. It has been found to inhibit cancer cell growth and induce apoptosis, or programmed cell death. The mechanism for this effect appears to be due to the ability of the bromine atom to react with hydrochloric acid, which leads to an increase in reactive oxygen species that can cause oxidative stress and DNA damage. This compound has also been shown to inhibit the growth of bacterial strains by interfering with their energy metabolism through inhibition of cycle analysis, molecular modeling, and fluorescence probe studies.

Purity: Min. 95%

Ref: 3D-FB38417

2-Bromo-3'-nitroacetophenone

Controlled Product

CAS: 2227-64-7

Applications 2-Bromo-3'-nitroacetophenone is a reagent used the preparation of arylthiazolidinone derivatives which have BRD4 bromodomain inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zhao, L., et al.: J. Med. Chem., 56, 3833 (2013);

Formula: C₈H₆BrNO₃

Color and Shape: Neat

Molecular weight: 244.04

Ref: TR-B688085