CAS 2227480-51-3

Ponatinib N-Oxide

CAS: 2227480-51-3

Formula: C₂₉H₂₇F₃N₆O₂

Color and Shape: Yellow Solid

Molecular weight: 548.57

Ref: 4Z-P-123004

Ponatinib N-Oxide

Controlled Product

CAS: 2227480-51-3

Applications Ponatinib N-Oxide is derived from Ponatinib (P688250), which is a tyrosine kinase inhibitors (TKI) and used to treat chronic myeloid leukemia (CML) (1,2,3). Ponatinib is also used in combination with other drugs, such as forskolin, to combat TKI resistance in patient with CML (3), targeted drug in small-cell lung cancer. Potent FAK inhibitor. FGFR/VEGFR/Bcr-Abl inhibitor. It is a COVID19-related research product.
References De L., et al.: J. Pharmacol. Exp. Ther., 363, 12-19 (2017), Arts, F. A., et al.: Hum. Mol. Genet., 26, 1801-1810 (2017)

Formula: C₂₉H₂₇F₃N₆O₂

Color and Shape: Neat

Molecular weight: 548.56

Ref: TR-P688260

Ponatinib N-Oxide

CAS: 2227480-51-3

Formula: C₂₉H₂₇F₃N₆O₂

Molecular weight: 548.57

Ref: ST-EA-CP-P94006