CAS 22280-02-0

4-Hydroxy-3-methylpyridine

Description:

4-Hydroxy-3-methylpyridine, with the CAS number 22280-02-0, is an organic compound that belongs to the class of pyridine derivatives. It features a hydroxyl group (-OH) and a methyl group (-CH3) attached to the pyridine ring, specifically at the 4 and 3 positions, respectively. This compound is typically a colorless to pale yellow liquid or solid, depending on its form and purity. It is known for its role in various chemical reactions and as an intermediate in the synthesis of pharmaceuticals and agrochemicals. The presence of the hydroxyl group contributes to its polar nature, enhancing its solubility in polar solvents like water and alcohols. Additionally, 4-hydroxy-3-methylpyridine exhibits weak acidic properties due to the hydroxyl group, which can participate in hydrogen bonding. Its chemical reactivity allows it to undergo various transformations, making it a valuable compound in organic synthesis and research. Safety data should be consulted for handling and storage, as with all chemical substances.

Formula: C₆H₇NO

InChI: InChI=1/C6H7NO/c1-5-4-7-3-2-6(5)8/h2-4H,1H3,(H,7,8)

SMILES: Cc1c[nH]ccc1=O

Synonyms:

• 3-Methylpyridin-4-ol
• 4-Pyridinol, 3-Methyl-
• 3-methylpyridin-4(1H)-one
• 3-Methyl-4-Hydroxypyridine

3-Methylpyridin-4-ol

CAS: 22280-02-0

Formula: C₆H₇NO

Purity: 95%

Color and Shape: Solid

Molecular weight: 109.1259

Ref: IN-DA0033R7

4-Hydroxy-3-methylpyridine

CAS: 22280-02-0

4-Hydroxy-3-methylpyridine

Purity: 97%

Color and Shape: Solid

Molecular weight: 109.13g/mol

Ref: 54-OR42109

4-Hydroxy-3-methylpyridine

Controlled Product

CAS: 22280-02-0

Applications 4-Hydroxy-3-methylpyridine, is an building block used in the chemical synthesis of various pharmaceutical and biologically active compounds. It is an intermediate for the synthesis of second generation agonist of the orphan G-protein coupled receptor GPR119, for the treatment of diabetes.
References Graeme, S., et al.: Bioorg. Med. Chem. Lett., 22, 1750 (2012);

Formula: C₆H₇NO

Color and Shape: Neat

Molecular weight: 109.126

Ref: TR-H948075

3-Methyl-4-hydroxypyridine

CAS: 22280-02-0

Formula: C₆H₇NO

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 109.128

Ref: 10-F076329