CAS 2228857-34-7

Azadibenzocyclooctyne-PEG1-N-hydroxysuccinimidyl ester

Description:

Azadibenzocyclooctyne-PEG1-N-hydroxysuccinimidyl ester is a bioorthogonal chemical compound primarily used in bioconjugation applications, particularly in the field of chemical biology and drug development. This compound features a strained alkyne moiety, which allows for rapid and selective reactions with azides through the click chemistry approach, facilitating the labeling of biomolecules. The PEG (polyethylene glycol) linker enhances solubility and biocompatibility, making it suitable for use in aqueous environments and biological systems. The N-hydroxysuccinimidyl (NHS) ester group is reactive towards amines, enabling the conjugation of the compound to proteins, peptides, or other biomolecules. This characteristic is particularly valuable for creating stable conjugates for imaging, therapeutic, or diagnostic purposes. Overall, the unique structural features of Azadibenzocyclooctyne-PEG1-N-hydroxysuccinimidyl ester make it a versatile tool in the development of targeted therapies and molecular probes in research and clinical applications.

Formula: C₂₈H₂₇N₃O₇

Synonyms:

• DBCO-NH-PEG1-CH2CH2COONHS ester
• Azadibenzocyclooctyne-PEG1-N-hydroxysuccinimidyl ester
• DBCO-PEG1-NHS Ester

DBCO-PEG1-NHS ester

CAS: 2228857-34-7

Formula: C₂₈H₂₇N₃O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 517.5299

Ref: IN-DA01JOTM

DBCO-PEG1-NHS ester

CAS: 2228857-34-7

DBCO-PEG1-NHS ester

Purity: 98%

Molecular weight: 517.53g/mol

Ref: 54-OR1007676

DBCO-PEG1-NHS ester

CAS: 2228857-34-7

DBCO-PEG1-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

Formula: C₂₈H₂₇N₃O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 517.53

Ref: TM-T17779