CAS 22298-29-9: betamethasone 17-benzoate

Description: Betamethasone 17-benzoate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is derived from betamethasone, a potent glucocorticoid, and is characterized by the presence of a benzoate ester at the 17-position. This modification enhances its lipophilicity, allowing for improved skin penetration and prolonged action when used in topical formulations. The compound is typically a white to off-white crystalline powder, and it is soluble in organic solvents such as ethanol and acetone, but has limited solubility in water. Betamethasone 17-benzoate is commonly used in dermatological preparations to treat various skin conditions, including eczema, psoriasis, and dermatitis, due to its ability to reduce inflammation and suppress immune responses. Its pharmacological effects are mediated through the modulation of gene expression, leading to decreased production of pro-inflammatory cytokines. As with other corticosteroids, its use should be carefully monitored to avoid potential side effects, including skin atrophy and systemic absorption, especially with prolonged use.

Formula: C₂₉H₃₃FO₆

InChI: InChI=1S/C29H33FO6/c1-17-13-22-21-10-9-19-14-20(32)11-12-26(19,2)28(21,30)23(33)15-27(22,3)29(17,24(34)16-31)36-25(35)18-7-5-4-6-8-18/h4-8,11-12,14,17,21-23,31,33H,9-10,13,15-16H2,1-3H3/t17-,21-,22-,23-,26-,27-,28-,29-/m0/s1

InChI key: InChIKey=SOQJPQZCPBDOMF-YCUXZELOSA-N

SMILES: O=C1C=CC2(C(=C1)CCC3C4CC(C)C(OC(=O)C=5C=CC=CC5)(C(=O)CO)C4(C)CC(O)C32F)C

Synonyms:

• (11Beta,16Beta)-9-Fluoro-11,21-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Benzoate
• (11β,16β)-17-(Benzoyloxy)-9-fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
• (8Xi,10Xi,11Beta,13Xi,16Beta)-9-Fluoro-11,21-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Benzoate
• Bebate
• Beben
• Benisone
• Betamethasone Benzoate
• Euvaderm
• Flurobate
• Ms 1112
• Parbetan
• Pregna-1,4-diene-3,20-dione, 17-(benzoyloxy)-9-fluoro-11,21-dihydroxy-16-methyl-, (11β,16β)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16β-methyl-, 17-benzoate
• Uticort
• W 5975
• Betamethasone 17-benzoate

Betamethasone Benzoate

CAS: 22298-29-9

Halogenated derivatives of adrenal cortical hormones

• Formula: C₂₉H₃₃FO₆
• Color and Shape: White Powder
• Molecular weight: 496.22612

Betamethasone 17-benzoate

CAS: 22298-29-9

Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of …

• Formula: C₂₉H₃₃FO₆
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 496.57

Betamethasone 17-Benzoate

CAS: 22298-29-9

• Formula: C₂₉H₃₃FO₆
• Color and Shape: Neat

Betamethasone 17-benzoate

CAS: 22298-29-9

Please enquire for more information about Betamethasone 17-benzoate including the price, delivery time and more …

• Formula: C₂₉H₃₃FO₆
• Purity: Min. 95%
• Molecular weight: 496.6 g/mol

Betamethasone benzoate

CAS: 22298-29-9

Betamethasone benzoate is a steroid that belongs to the group of corticosteroids. The biological properties …

• Formula: C₂₉H₃₃FO₆
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 496.57 g/mol