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CAS 22298-29-9

:

betamethasone 17-benzoate

Description:
Betamethasone 17-benzoate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is derived from betamethasone, a potent glucocorticoid, and is characterized by the presence of a benzoate ester at the 17-position. This modification enhances its lipophilicity, allowing for improved skin penetration and prolonged action when used in topical formulations. The compound is typically a white to off-white crystalline powder, and it is soluble in organic solvents such as ethanol and acetone, but has limited solubility in water. Betamethasone 17-benzoate is commonly used in dermatological preparations to treat various skin conditions, including eczema, psoriasis, and dermatitis, due to its ability to reduce inflammation and suppress immune responses. Its pharmacological effects are mediated through the modulation of gene expression, leading to decreased production of pro-inflammatory cytokines. As with other corticosteroids, its use should be carefully monitored to avoid potential side effects, including skin atrophy and systemic absorption, especially with prolonged use.
Formula:C29H33FO6
InChI:InChI=1/C29H33FO6/c1-17-13-22-21-10-9-19-14-20(32)11-12-26(19,2)28(21,30)23(33)15-27(22,3)29(17,24(34)16-31)36-25(35)18-7-5-4-6-8-18/h4-8,11-12,14,17,21-23,31,33H,9-10,13,15-16H2,1-3H3/t17-,21-,22-,23-,26-,27-,28-,29-/m0/s1
InChI key:InChIKey=SOQJPQZCPBDOMF-YCUXZELOSA-N
SMILES:O(C(=O)C1=CC=CC=C1)[C@@]2(C(CO)=O)[C@]3(C)[C@@](C[C@@H]2C)([C@]4([C@](F)([C@@H](O)C3)[C@]5(C)C(CC4)=CC(=O)C=C5)[H])[H]
Synonyms:
  • (11Beta,16Beta)-9-Fluoro-11,21-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Benzoate
  • (11β,16β)-17-(Benzoyloxy)-9-fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
  • (8Xi,10Xi,11Beta,13Xi,16Beta)-9-Fluoro-11,21-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Benzoate
  • Bebate
  • Beben
  • Benisone
  • Betamethasone Benzoate
  • Euvaderm
  • Flurobate
  • Ms 1112
  • See more synonyms
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Found 4 products.
  • CymitQuimica logo
    USP
    + Info

    Betamethasone Benzoate

    CAS:
    Halogenated derivatives of adrenal cortical hormones
    Formula:C29H33FO6
    Color and Shape:White Powder
    Molecular weight:496.22612

    Ref: 45-1067307

  • Betamethasone 17-benzoate
    Targetmol
    + Info

    Betamethasone 17-benzoate

    CAS:
    <p>Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of recurrent aphothous ulcers (RAU).</p>
    Formula:C29H33FO6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:496.57

    Ref: TM-T16152

  • Betamethasone 17-Benzoate
    TRC
    + Info

    Betamethasone 17-Benzoate

    Controlled Product
    CAS:
    Formula:C29H33FO6
    Color and Shape:Neat

    Ref: TR-B327995

    100mg
    1,933.00€
  • Betamethasone 17-benzoate
    Biosynth
    + Info

    Betamethasone 17-benzoate

    Controlled Product
    CAS:
    <p>Betamethasone 17-benzoate is a synthetic corticosteroid with antiinflammatory and antipruritic properties. It is available in the form of an ointment, cream, or lotion. Betamethasone 17-benzoate has been shown to be effective in the treatment of inflammatory bowel disease and leishmania. Betamethasone binds to the glucocorticoid receptor and inhibits the production of prostaglandins involved in inflammation. This drug also has a low potency, which means that it takes more time for this drug to have an effect on the body.</p>
    Formula:C29H33FO6
    Purity:Min. 95%
    Molecular weight:496.6 g/mol

    Ref: 3D-XAA29829

    250mg
    863.00€
    500mg
    1,179.00€