CAS 2230253-82-2

PKI-166 hydrochloride

CAS: 2230253-82-2

EGFR-kinase inhibitor, IC50 0.7 nM, >3000x selective, cuts metastasis and angiogenesis in mice, antihypertensive, oral use.

Formula: C₂₀H₁₉ClN₄O

Color and Shape: Solid

Molecular weight: 366.85

Ref: TM-T36643

PKI-166 hydrochloride

CAS: 2230253-82-2

PKI-166 hydrochloride is a peptide that has been generated and characterized to study protein interactions. It is an inhibitor of ion channels and has been shown to inhibit the activity of L-type calcium channels in rat brain synaptosomes. PKI-166 hydrochloride also inhibits the binding of β2 adrenergic receptor ligands to their receptors, as well as inhibiting the phosphorylation of proteins by tyrosine kinase.
PKI-166 hydrochloride is a white crystalline powder with a purity of >98%. The molecular weight is 1,494 Da.

Formula: C₂₀H₁₉ClN₄O

Purity: Min. 95%

Molecular weight: 366.8 g/mol

Ref: 3D-FPD25382