CAS 223132-37-4
:Inolitazone
Description:
Inolitazone, with the CAS number 223132-37-4, is a chemical compound that belongs to the class of thiazolidinediones, which are primarily known for their role in the treatment of type 2 diabetes. This compound functions as a selective agonist for the peroxisome proliferator-activated receptor gamma (PPAR-γ), which plays a crucial role in glucose and lipid metabolism. Inolitazone exhibits anti-inflammatory properties and has been studied for its potential effects on insulin sensitivity and weight management. Its molecular structure includes a thiazolidinedione core, which is characteristic of its class, contributing to its biological activity. The compound has shown promise in preclinical studies, indicating potential benefits in metabolic disorders. However, as with many pharmacological agents, the safety profile, efficacy, and long-term effects in humans require thorough investigation through clinical trials. Overall, Inolitazone represents a significant area of interest in metabolic research and drug development.
Formula:C27H26N4O4S
Synonyms:- 5-[[4-[[6-(4-Amino-3,5-dimethylphenoxy)-1-methyl-1H-benzimidazol-2-yl]methoxy]phenyl]methyl]-2,4-thiazolidinedione
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Found 3 products.
Inolitazone
CAS:Controlled Product<p>Inolitazone is a potent and selective activator of the IKr potassium channel. It has an IC50 of 2.6 nM in whole-cell patch-clamp recordings on rat brain ventricular myocytes and a Ki of 0.5 nM in binding assays with purified IKr receptor protein. Inolitazone binds to the activation site of the IKr channel, inducing hyperpolarization by increasing K+ efflux from the cell.</p>Formula:C27H26N4O4SPurity:Min. 95%Molecular weight:502.6 g/molInolitazone
CAS:Inolitazone (RS5444) a high-affinity PPARγ agonist. Inolitazone exhibits IC50 for growth inhibition is ~0.8 nM in vitro.Formula:C27H26N4O4SPurity:99.41% - 99.53%Color and Shape:SolidMolecular weight:502.58
