CAS 22316-55-8: Desmethylclobazam

Description:Desmethylclobazam, with the CAS number 22316-55-8, is a chemical compound that is a derivative of clobazam, a benzodiazepine used primarily as an anxiolytic and anticonvulsant. Desmethylclobazam is characterized by its structural modification, specifically the absence of a methyl group at the nitrogen atom in the benzodiazepine ring. This alteration influences its pharmacological properties, including its potency and efficacy. The compound exhibits a high affinity for the GABA-A receptor, which is crucial for its anxiolytic and anticonvulsant effects. Desmethylclobazam is typically administered in a pharmaceutical context and is known for its relatively long half-life, contributing to its sustained therapeutic effects. Additionally, it may undergo metabolic processes in the liver, leading to the formation of active metabolites. As with other benzodiazepines, caution is advised regarding potential dependence and withdrawal symptoms with prolonged use. Overall, desmethylclobazam represents an important compound in the study of benzodiazepine pharmacology and its applications in treating various neurological disorders.

Formula:C₁₅H₁₁ClN₂O₂

InChI:InChI=1S/C15H11ClN2O2/c16-10-6-7-12-13(8-10)18(11-4-2-1-3-5-11)15(20)9-14(19)17-12/h1-8H,9H2,(H,17,19)

InChI key:InChIKey=RRTVVRIFVKKTJK-UHFFFAOYSA-N

SMILES:O=C1NC2=CC=C(Cl)C=C2N(C=3C=CC=CC3)C(=O)C1

Synonyms:
1H-1,5-Benzodiazepine-2,4(3H,5H)-dione, 8-chloro-1-phenyl-
7-Chloro-5-phenyl-1,2,4,5-tetrahydro-3H-1,5-benzodiazepine-2,4-dione
7-Chloro-5-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione
Clofazin
Demethylclobazam
Desmethylclobazam
N-Demethylclobazam
N-Desmethylclobazam
Norclobazam
8-Chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione
See more synonyms
8-Chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione

Found 12 products.

Product data	Purity	Price range	Estimated delivery
Clobazam impurity A CRS REF: 41-Y0000241CAS: 22316-55-8	- - -	115.00 €	Mon 14 Apr 25
Clobazam Related Compound A (8-Chloro-1-phenyl-1,5-dihydro-2H-benzo[b][1,4]diazepine-2,4(3H)-dione) REF: 45-1138314CAS: 22316-55-8	- - -	1,357.00 €	Tue 15 Apr 25
7-Chloro-5-phenyl-1,5-dihydro-3H-1,5-benzodiazepine-2,4-dione (Norclobazam) REF: 86-MM0910.01CAS: 22316-55-8	- - -	To inquire	Mon 21 Apr 25
7-Chloro-5-phenyl-1,5-dihydro-3H-1,5-benzodiazepine-2,4-dione (Norclobazam) REF: 86-MM0910.01-0025CAS: 22316-55-8	- - -	To inquire	Mon 21 Apr 25
N-Desmethyl Clobazam REF: TR-D291540CAS: 22316-55-8	- - -	319.00 €~2,158.00 €	Mon 28 Apr 25
N-Desmethyl Clobazam-13C6 (1.0 mg/mL in Acetonitrile) REF: TR-KIT1651CAS: 22316-55-8	- - -	952.00 €	Tue 27 May 25
N-Desmethyl Clobazam (100 µg/mL in Acetonitrile) REF: TR-KIT1650CAS: 22316-55-8	- - -	266.00 €	Tue 27 May 25
N-Desmethyl Clobazam-13C6 (100 µg/mL in Acetonitrile) REF: TR-KIT1652CAS: 22316-55-8	- - -	292.00 €	Tue 27 May 25
N-Desmethyl Clobazam-13C6 REF: TR-D291543CAS: 22316-55-8	- - -	564.00 €~3,851.00 €	Tue 27 May 25
N-Desmethyl Clobazam (1.0mg/ml in Acetonitrile) REF: TR-KIT4025CAS: 22316-55-8	- - -	2,353.00 €	Tue 27 May 25
N-Desmethyl clobazam REF: 3D-FD21253CAS: 22316-55-8	Min. 95%	To inquire	Wed 28 May 25
7-chloro-1-5-dihydro-5-phenyl-1,5-benzodiazepine-2,4(3H)-dione REF: 47-470CAS: 22316-55-8	- - -	- - -	Discontinued product