CAS 22316-59-2

2-Methyl-3-(4-methylphenyl)-4(3H)-quinazolinone

Description:

2-Methyl-3-(4-methylphenyl)-4(3H)-quinazolinone, identified by its CAS number 22316-59-2, is a heterocyclic organic compound belonging to the quinazolinone class. This compound features a quinazolinone core, which is characterized by a fused benzene and pyrimidine ring structure, with specific substitutions that enhance its chemical properties. The presence of a methyl group at the 2-position and a para-methylphenyl group at the 3-position contributes to its unique reactivity and potential biological activity. Typically, quinazolinones exhibit a range of pharmacological properties, including anti-inflammatory, analgesic, and anticancer activities, making them of interest in medicinal chemistry. The compound is likely to be a solid at room temperature, with moderate solubility in organic solvents. Its molecular structure allows for various interactions, including hydrogen bonding and π-π stacking, which can influence its behavior in biological systems. As with many organic compounds, safety data should be consulted for handling and usage, as well as potential environmental impacts.

Formula: C₁₆H₁₄N₂O

InChI: InChI=1S/C16H14N2O/c1-11-7-9-13(10-8-11)18-12(2)17-15-6-4-3-5-14(15)16(18)19/h3-10H,1-2H3

InChI key: InChIKey=ZDTGZJXXQHUFIR-UHFFFAOYSA-N

SMILES: O=C1N(C(C)=NC=2C1=CC=CC2)C3=CC=C(C)C=C3

Synonyms:

• 2-Methyl-3-(4-methylphenyl)-4(3H)-quinazolinone
• 4(3H)-Quinazolinone, 2-methyl-3-(4-methylphenyl)-
• 2-Methyl-3-(4-methylphenyl)-3,4-dihydroquinazolin-4-one
• 4(3H)-Quinazolinone, 2-methyl-3-p-tolyl-
• 2-Methyl-3-p-tolyl-4(3H)-quinazolinone

2-Methyl-3-(4-methylphenyl)-3,4-dihydroquinazolin-4-one

Controlled Product

CAS: 22316-59-2

2-Methyl-3-(4-methylphenyl)-3,4-dihydroquinazolin-4-one is a benzoyl peroxide derivative that is used as a thermal stabilizer in polymers. It is prepared by bromination of 2-methyl-3-(4-methylphenyl) quinazoline and then reacting the bromine with benzoyl peroxide. 2-Methyl-3-(4-methylphenyl)-3,4-dihydroquinazolin-4-one has been shown to be an efficient catalyst for the hydrobromic acid catalyzed conversion of benzoyl chlorides to their corresponding peroxyacids. 2mMDQQ has been studied for its ability to inhibit the growth of bacteria such as Staphylococcus aureus and Streptococcus pyogenes, as well as Candida albicans yeast cells.

Formula: C₁₆H₁₄N₂O

Purity: Min. 95%

Molecular weight: 250.29 g/mol

Ref: 3D-XAA31659