CAS 22333-58-0

9-Hydroxy-alpha-lapachone

Description:

9-Hydroxy-alpha-lapachone is a chemical compound derived from lapachone, a natural product found in the bark of the Tabebuia tree. It is characterized by its hydroxyl group at the 9-position, which contributes to its biological activity. This compound exhibits potential pharmacological properties, including anti-cancer, anti-inflammatory, and antioxidant activities, making it of interest in medicinal chemistry and drug development. The structure of 9-hydroxy-alpha-lapachone includes a naphthoquinone core, which is significant for its reactivity and interaction with biological systems. Its solubility and stability can vary depending on the solvent and conditions, influencing its bioavailability and efficacy. Additionally, research has indicated that it may induce apoptosis in cancer cells and modulate various signaling pathways, highlighting its potential therapeutic applications. As with many compounds, further studies are necessary to fully elucidate its mechanisms of action and potential side effects.

9-Hydroxy-α-Lapachone

CAS: 22333-58-0

Formula: C₁₅H₁₄O₄

Molecular weight: 258.2693

Ref: IN-DA00C4Q8

9-Hydroxy-α-lapachone

CAS: 22333-58-0

9-Hydroxy-alpha-lapachone inhibits H. pylori growth & LPS-induced NO in RAW 264.7 cells, both with IC50 of 4.64 µM; may also reduce inflammation.

Formula: C₁₅H₁₄O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 258.27

Ref: TM-TN3318

9-Hydroxy-α-lapachone

CAS: 22333-58-0

Formula: C₁₅H₁₄O₄

Purity: 95%~99%

Color and Shape: Yellow powder

Molecular weight: 258.273

Ref: BP-SBP01713

9-Hydroxy-α-lapachone

Controlled Product

CAS: 22333-58-0

9-Hydroxy-alpha-lapachone is a natural naphthoquinone derivative, which is extracted from the heartwood of the Lapacho tree (Tabebuia sp.). This compound exhibits a variety of biological activities due to its ability to modulate multiple cellular pathways. The mode of action primarily involves the induction of oxidative stress within cancer cells through the generation of reactive oxygen species (ROS), leading to apoptosis. It also inhibits topoisomerase enzymes, which are crucial for DNA replication and repair, thereby interfering with cancer cell proliferation.

Formula: C₁₅H₁₄O₄

Purity: Min. 95%

Molecular weight: 258.27 g/mol

Ref: 3D-XAA33358