CAS 223387-75-5

Glycine, N-[(1-chloro-4-hydroxy-3-isoquinolinyl)carbonyl]-

Description:

Glycine, N-[(1-chloro-4-hydroxy-3-isoquinolinyl)carbonyl]- is a synthetic compound that features a glycine moiety linked to a chlorinated isoquinoline derivative. This compound is characterized by its unique structural components, which include a chloro group and a hydroxy group on the isoquinoline ring, contributing to its potential biological activity. The presence of the carbonyl group indicates that it may participate in various chemical reactions, such as nucleophilic attacks or condensation reactions. Glycine itself is the simplest amino acid, and its incorporation into this compound suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals. The compound may exhibit specific interactions with biological targets due to its structural features, making it of interest in drug discovery and development. Additionally, its solubility and stability in various solvents can influence its behavior in biological systems and its utility in research applications. Overall, this compound represents a fusion of amino acid chemistry and heterocyclic chemistry, highlighting the versatility of glycine derivatives in synthetic organic chemistry.

Formula: C₁₂H₉ClN₂O₄

Synonyms:

• [[(1-Chloro-4-hydroxyisoquinolin-3-yl)carbonyl]amino]acetic acid
• FG-2216
• BIQ
• FG 2216 (erythropoietic agent)
• FG-2216(IOX3
• FG2216;FG-2216;FG 2216
• (Z)-2-(((1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)(HYDROXY)METHYLENE)AMINO)ACETIC ACID
• YM 311
• FG2216
• CS-1687
• FG 2216
• (N-(1-chloro-4-hydroxy-isoquinoline-3-carbonyl)-amino)-acetic acid
• Glycine, N-[(1-chloro-4-hydroxy-3-isoquinolinyl)carbonyl]-
• N-[(1-Chloro-4-hydroxy-3-isoquinolinyl)carbonyl]glycine
• FG-2216 - YM 311

N-[(1-Chloro-4-hydroxy-3-isoquinolinyl)carbonyl]glycine

CAS: 223387-75-5

Formula: C₁₂H₉ClN₂O₄

Purity: 96%

Color and Shape: Solid

Molecular weight: 280.6639

Ref: IN-DA00392N

(1-Chloro-4-Hydroxyisoquinoline-3-Carbonyl)Glycine

CAS: 223387-75-5

(1-Chloro-4-Hydroxyisoquinoline-3-Carbonyl)Glycine

Purity: 99%

Molecular weight: 280.66g/mol

Ref: 54-OR1023779

FG-2216

CAS: 223387-75-5

FG-2216

Purity: ≥95%

Molecular weight: 280.66g/mol

Ref: 54-BUP15518

FG-2216

CAS: 223387-75-5

FG-2216 (YM-311) is a HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme; orally bioavailable and induced reversible and significant Epo induction in vivo.

Formula: C₁₂H₉ClN₂O₄

Purity: 97.1% - >99.99%

Color and Shape: Solid

Molecular weight: 280.66

Ref: TM-T2445

FG-2216

CAS: 223387-75-5

Formula: C₁₂H₉ClN₂O₄

Molecular weight: 280.67

Ref: 4Z-F-122001

FG 2216

Controlled Product

CAS: 223387-75-5

Applications FG 2216 is an erythropoietic agent which is orally active prolyl-hydroxylase inhibitor which increases erythropoietin production in end-stage kidney disease.
References Bernhardt, W., et al.: J. Am. Soc. Nephrol., 21, 2151 (2010)

Formula: C₁₂H₉ClN₂O₄

Color and Shape: White

Molecular weight: 280.664

Ref: TR-F329000

N-[(1-Chloro-4-hydroxy-3-isoquinolinyl)carbonyl]glycine

CAS: 223387-75-5

Purity: 99%

Molecular weight: 280.6600037

Ref: 10-F862479

FG-2216

CAS: 223387-75-5

FG-2216 is a peptide that activates the G protein-coupled receptor, leading to increased intracellular calcium. FG-2216 is a potent agonist of the GPRC6A receptor and has been shown to inhibit pain perception in animal models. FG-2216 has been shown to have no effect on ion channels and does not affect cellular proliferation or migration. FG-2216 may be useful as a research tool for studying the function of the GPRC6A receptor in animal models.

Formula: C₁₂H₉ClN₂O₄

Purity: Min. 95%

Molecular weight: 280.66 g/mol

Ref: 3D-YIA38775