CAS 2234273-72-2

1H-Pyrrole-2-carboxamide, N-[(1S)-2-amino-1-[4-(hydroxymethyl)-2-thiazolyl]ethyl]-5-[3-fluoro-4-(trifluoromethyl)phenyl]-

Description:

1H-Pyrrole-2-carboxamide, N-[(1S)-2-amino-1-[4-(hydroxymethyl)-2-thiazolyl]ethyl]-5-[3-fluoro-4-(trifluoromethyl)phenyl]- is a complex organic compound characterized by its unique structural features, including a pyrrole ring, a carboxamide functional group, and a thiazole moiety. The presence of a fluorinated phenyl group enhances its potential biological activity and lipophilicity, which can influence its pharmacokinetic properties. The compound's thiazole and hydroxymethyl substituents may contribute to its reactivity and interactions with biological targets. As a result, it may exhibit specific pharmacological effects, making it of interest in medicinal chemistry and drug development. The stereochemistry indicated by the (1S) configuration suggests that the compound may have chiral properties, which can affect its biological activity and interactions. Overall, this compound's intricate structure and functional groups suggest potential applications in therapeutic contexts, although further studies would be necessary to elucidate its specific properties and mechanisms of action.

Formula: C₁₈H₁₆F₄N₄O₂S

Synonyms:

• 1H-Pyrrole-2-carboxamide, N-[(1S)-2-amino-1-[4-(hydroxymethyl)-2-thiazolyl]ethyl]-5-[3-fluoro-4-(trifluoromethyl)phenyl]-

NBD-14189

CAS: 2234273-72-2

NBD-14189: Potent HIV-1 entry blocker, binds gp120, IC50: 89 nM, strong antiviral (EC50 <200 nM).

Formula: C₁₈H₁₆F₄N₄O₂S

Color and Shape: Solid

Molecular weight: 428.40

Ref: TM-T62340