CAS 223463-13-6

5-Bromo-2-iodopyridine

Description:

5-Bromo-2-iodopyridine is a heterocyclic organic compound characterized by the presence of both bromine and iodine substituents on a pyridine ring. Its molecular structure consists of a six-membered aromatic ring containing five carbon atoms and one nitrogen atom, with bromine attached to the fifth carbon and iodine to the second carbon. This compound is typically a pale yellow to brown solid and is soluble in organic solvents such as dichloromethane and dimethyl sulfoxide, but has limited solubility in water. 5-Bromo-2-iodopyridine is notable for its reactivity, particularly in cross-coupling reactions, making it valuable in the synthesis of various pharmaceuticals and agrochemicals. Its unique halogen substituents enhance its electrophilic character, facilitating nucleophilic substitutions. Additionally, it is important to handle this compound with care due to the potential toxicity associated with halogenated compounds. As with many organic compounds, proper safety protocols should be followed during its use and handling in laboratory settings.

Formula: C₅H₃BrIN

InChI: InChI=1S/C5H3BrIN/c6-4-1-2-5(7)8-3-4/h1-3H

InChI key: InChIKey=HSNBRDZXJMPDGH-UHFFFAOYSA-N

SMILES: BrC=1C=CC(I)=NC1

Synonyms:

• 2-Iodo-5-Bromopyridine
• 5-Bromo-2-iodo-pyridine
• Pyridine, 5-bromo-2-iodo-
• 5-Bromo-2-iodopyridine
• 5-bromo-2-iodopyridine 97% 5g
• 5-Bromo-2-Iodopyridine99%
• 5-BROMO-2-IDIOPYRIDINE
• 5-bromo-2-lodopyridine
• 5-Bromo-2-iodopyridine, 98+%
• 5-BROMO-2-IODOPYRIDINE 97%

5-Bromo-2-iodopyridine

CAS: 223463-13-6

Formula: C₅H₃BrIN

Purity: >97.0%(GC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 283.89

Ref: 3B-B2877

5-Bromo-2-iodopyridine, 98%

CAS: 223463-13-6

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₅H₃BrIN

Purity: 98%

Color and Shape: White to pale cream, Crystals or powder or crystalline powder or flakes

Molecular weight: 283.89

Ref: 02-L19610

5-Bromo-2-iodopyridine

CAS: 223463-13-6

Formula: C₅H₃BrIN

Purity: 98%

Color and Shape: Solid

Molecular weight: 283.8925

Ref: IN-DA0037JI

5-Bromo-2-iodopyridine

CAS: 223463-13-6

Formula: C₅H₃BrIN

Molecular weight: 283.89

Ref: 7W-GK2528

5-Bromo-2-iodopyridine

CAS: 223463-13-6

5-Bromo-2-iodopyridine

Formula: C₅H₃BrIN

Purity: 98%

Color and Shape: white solid

Molecular weight: 283.89g/mol

Ref: 54-OR1964

5-Bromo-2-iodopyridine

CAS: 223463-13-6

Formula: C₅H₃BrIN

Purity: 98%

Color and Shape: Solid

Molecular weight: 283.894

Ref: 10-F023885

5-Bromo-2-iodopyridine

Controlled Product

CAS: 223463-13-6

Stability Light Sensitive
Applications 5-Bromo-2-iodopyridine is used to prepare substituted (pyridin-​3-​yl)​phenyloxazolidinones as antibacterial agents. It is also used to synthesize indole-​based bisamidine antibiotics.
References Reck, F., et al.: J. Med. Chem., 50, 4868 (2007); Williams, J., et al.: Bioorg. Med. Chem., 21, 7790 (2013)

Formula: C₅H₃BrIN

Color and Shape: Neat

Molecular weight: 283.89

Ref: TR-B687630

5-Bromo-2-iodopyridine

CAS: 223463-13-6

5-Bromo-2-iodopyridine is an antibiotic that is used to treat bacterial infections. It has been shown to inhibit the growth of bacteria by binding to the 50S ribosomal subunit. This drug also has a toxic effect on respiratory system cells, which may be due to its ability to induce apoptosis. 5-Bromo-2-iodopyridine interacts with DNA in a triazine ring and inhibits bacterial growth by inhibiting protein synthesis. The drug binds to the 50S ribosomal subunit at a site that is different from that of rifampin and other antibiotics. The reaction is catalyzed by palladium at high temperatures and takes place in organic solvents such as chloroform or benzene. This synthetic process can be made more efficient by using inexpensive starting materials, such as bromine, iodine, and acetone, rather than expensive starting materials like platinum or gold salts.

Formula: C₅H₃BrIN

Purity: Min. 95%

Color and Shape: Slightly Yellow Powder

Molecular weight: 283.89 g/mol

Ref: 3D-FB07067