CAS 22350-41-0

trans-Vitamin D3

Description:

Trans-Vitamin D3, also known as trans-cholecalciferol, is a secosteroid and a form of vitamin D that plays a crucial role in calcium and phosphate metabolism in the body. It is characterized by its unique molecular structure, which includes a steroid backbone with a broken ring, allowing it to interact effectively with vitamin D receptors. This compound is typically synthesized in the skin upon exposure to ultraviolet B (UVB) radiation from sunlight, although it can also be obtained through dietary sources and supplements. Trans-Vitamin D3 is known for its role in promoting bone health, immune function, and overall well-being. Its solubility in lipids and oils makes it bioavailable when consumed in dietary fats. The compound is stable under normal conditions but can degrade when exposed to excessive heat, light, or oxygen. The CAS number 22350-41-0 specifically identifies this compound, facilitating its recognition in scientific literature and regulatory contexts. Overall, trans-Vitamin D3 is essential for maintaining optimal health and preventing deficiencies that can lead to various health issues.

Formula: C₂₇H₄₄O

InChI: InChI=1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13+/t21-,24+,25-,26+,27-/m1/s1

InChI key: InChIKey=QYSXJUFSXHHAJI-FVUVGDFOSA-N

SMILES: C[C@@]12[C@](\C(=C\C=C/3\C(=C)CC[C@H](O)C3)\CCC1)(CC[C@@]2([C@@H](CCCC(C)C)C)[H])[H]

Synonyms:

• (1S,3E)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-Dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylenecyclohexanol
• 5,6-trans-Cholecalciferol
• 5,6-trans-Vitamin D3
• 5,6-trans-Vitamin D₃
• 9,10-Secocholesta-5,7,10(19)-trien-3-ol, (3β,5E,7E)-
• 9,10-Secocholesta-5,7,10(19)-trien-3β-ol, (E,E)-
• Cholecalciferol Impurity A
• Cyclohexanol, 3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1S,3E)-
• trans-Vitamin D₃
• trans-Vitamin D3

CHOLECALCIFEROL IMPURITY A CRS

CAS: 22350-41-0

CHOLECALCIFEROL IMPURITY A CRS

Ref: 41-Y0002328

trans-Cholecalciferol ((S,E)-3-(2-((1R,3aS,7aR,E)-7a-methyl-1-((R)-6-methylheptan-2-yl)octahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexan-1-ol)

CAS: 22350-41-0

Other cyclanic, cyclenic or cycloterpenic alcohols and their halogenated, sulfonated, nitrated or nitrosated derivatives

Formula: C₂₇H₄₄O

Color and Shape: Off-White Solid

Molecular weight: 384.33922

Ref: 45-1A02060

5,6-trans-Vitamin D3

CAS: 22350-41-0

5,6-trans-Vitamin D3

Purity: ≥95%

Molecular weight: 384.64g/mol

Ref: 54-BUP06944

Cholecalciferol EP Impurity A (5,6-trans-Cholecalciferol, 5,6-trans-Vitamin D3)

CAS: 22350-41-0

Formula: C₂₇H₄₄O

Color and Shape: White To Off-White Solid

Molecular weight: 384.65

Ref: 4Z-C-516

Cholecalciferol EP Impurity A

CAS: 22350-41-0

Formula: C₂₇H₄₄O

Molecular weight: 384.65

Ref: ST-EA-CP-C127001

5,6-trans-Vitamin D3

CAS: 22350-41-0

5,6-trans-Vitamin D3（5,6-trans-Cholecalciferol） is an isoform of Vitamin D3, which is converted from Vitamin D3 on the skin surface after light exposure.

Formula: C₂₇H₄₄O

Purity: 98.23%

Color and Shape: Solid

Molecular weight: 384.64

Ref: TM-T35501

5,6-trans-Vitamin D3, ~90%

Controlled Product

CAS: 22350-41-0

Impurity Cholecalciferol EP Impurity A
Stability Light Sensitive, Temperature Sensitive
Applications 5,6-trans-Vitamin D3 (Cholecalciferol EP Impurity A) is the major photoisomer of Vitamin D3 analog, as an impurity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bikle, D., et al.: Biochemistry, 25, 1545 (1986), Webb, A., et al.: J. Clin. Endocrinol. Metab., 68, 882 (1989), Baran, D., et al.: J. Cell Biochem., 50, 124 (1992), Tian, X., et al.: J. Biol. Chem., 268, 14888 (1993),

Formula: C₂₇H₄₄O

Purity: ~90%

Color and Shape: White To Light Yellow

Molecular weight: 384.64

Ref: TR-V676065

Cholecalciferol impurity A

CAS: 22350-41-0

Cholecalciferol impurity A is a cholecalciferol impurity that is used in oral hypoglycaemic drugs. It has been shown to be effective in the treatment of type 1 and type 2 diabetes, as well as multiple sclerosis, rheumatoid arthritis, and other autoimmune diseases. Cholecalciferol impurity A binds to the response element for vitamin D3 and mediates gene expression. It also activates calcium-dependent signaling pathways, which are important for bone metabolism and the immune system. This drug has been shown to reduce disease activity by increasing blood levels of natriuretic peptide levels and reducing blood sampling times in animal models.

Formula: C₂₇H₄₄O

Purity: Min. 90 Area-%

Color and Shape: White Yellow Powder

Molecular weight: 384.64 g/mol

Ref: 3D-FC159094

(1S,3E)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol

CAS: 22350-41-0

Purity: 95%

Molecular weight: 384.6480103

Ref: 10-F863409