CAS 22365-13-5

Decarboxylated AdoMet

Description:

Decarboxylated AdoMet, also known as decarboxylated S-adenosylmethionine, is a derivative of S-adenosylmethionine (AdoMet), which is a key methyl donor in biological methylation reactions. This compound is characterized by the absence of a carboxyl group, which distinguishes it from its parent compound. It plays a significant role in various biochemical processes, including the synthesis of polyamines and the regulation of gene expression through methylation. Decarboxylated AdoMet is involved in the metabolism of amino acids and can influence cellular signaling pathways. Its structure typically includes an adenosine moiety linked to a methionine group, with the decarboxylation affecting its reactivity and biological function. This compound is of interest in research related to cellular metabolism, epigenetics, and potential therapeutic applications. As with many biochemical substances, its stability and reactivity can be influenced by environmental factors such as pH and temperature, making it important to consider these conditions in experimental settings.

Formula: C₁₄H₂₃N₆O₃S

InChI: InChI=1S/C14H23N6O3S/c1-24(4-2-3-15)5-8-10(21)11(22)14(23-8)20-7-19-9-12(16)17-6-18-13(9)20/h6-8,10-11,14,21-22H,2-5,15H2,1H3,(H2,16,17,18)/q+1/t8-,10-,11-,14-,24?/m1/s1

InChI key: InChIKey=ZUNBITIXDCPNSD-LSRJEVITSA-N

SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](C[S+](CCCN)C)[C@H]1O

Synonyms:

• S-Adenosyl-3-methylthiopropylamine
• Adenosine, 5′-[(3-aminopropyl)methylsulfonio]-5′-deoxy-
• 5′-[(3-Aminopropyl)methylsulfonio]-5′-deoxyadenosine
• S-Methyladenosylhomocysteamine
• (-)-S-Adenosyl-(5′)-3-methylthiopropylamine

Decarboxylated (S)-Adenosyl Methionine Trifluoromethanesulfonic Acid

CAS: 22365-13-5

Formula: C₁₄H₂₃N₆O₃S·CF₃O₃S

Color and Shape: Orange Solid

Molecular weight: 355.44 149.06

Ref: 4Z-A-106009

Decarboxylated (S)-Adenosyl Methionine Tritrifluoromethanesulfonic Acid

CAS: 22365-13-5

Formula: C₁₄H₂₃N₆O₃S·CF₃O₃S·2CHF₃O₃S

Molecular weight: 355.44 149.06 2*150.07

Ref: 4Z-A-106050

Decarboxylated S-Adenosylmethionine-13C-d3 Sulfate Salt

CAS: 22365-13-5, 67380-81-8

Formula: C₁₃₁₃CH₂₀D₃N₆O₃S·HSO₄H₂SO₄

Molecular weight: 359.45 97.06 98.07

Ref: 4Z-A-106032

Decarboxylated S-Adenosylmethionine-d3 Sulfate Salt

Controlled Product

CAS: 22365-13-5

Stability Hygroscopic
Applications Decarboxylated S-Adenosylmethionine-d3 is labelled decarboxylated S-adenosyl methionine (D222000) which is a substrate that is involved in the biosynthesis of polyamines including spermidine, spermine, and thermospermine.
References Takahashi,T., et al.: Ann. Bot., 105, 1 (2009); Wu, H., et al.: Biochem., 46, 8331 (2007); Pegg, A., et al.: Biochem., 28, 8446 (1989);

Formula: C₁₄H₂₀D₃N₆O₃S•HSO₄•x(H₂SO₄)

Color and Shape: Neat

Molecular weight: 358.45 + 97.07 + x(98.08)

Ref: TR-D222002

Decarboxylated S-Adenosylmethionine-d3 xSulfate Salt (>90%)

Controlled Product

CAS: 22365-13-5

Stability Hygroscopic
Applications Decarboxylated S-Adenosylmethionine-d3 is labelled decarboxylated S-adenosyl methionine (D222000) which is a substrate that is involved in the biosynthesis of polyamines including spermidine, spermine, and thermospermine.
References Takahashi,T., et al.: Ann. Bot., 105, 1 (2009); Wu, H., et al.: Biochem., 46, 8331 (2007); Pegg, A., et al.: Biochem., 28, 8446 (1989);

Formula: C₁₄H₂₀D₃N₆O₃S·HSO₄·xH₂SO₄

Purity: >90%

Color and Shape: Neat

Molecular weight: 358.45 + 97.07 + x(98.08)

Ref: TR-D222003

S-Adenosylmethioninamine

CAS: 22365-13-5

Formula: C₁₄H₂₃N₆O₃S

Molecular weight: 355.44

Ref: ST-EA-CP-A88019

Decarboxylated S-adenosylmethionine-d3 sulfuric acid

CAS: 22365-13-5

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Formula: C₁₄H₂₃N₆O₃S

Purity: Min. 95%

Molecular weight: 355.44 g/mol

Ref: 3D-XAA36513