CAS 223652-82-2

Garenoxacin mesylate

Description:

Garenoxacin mesylate is a synthetic fluoroquinolone antibiotic characterized by its broad-spectrum antibacterial activity, particularly against Gram-positive and Gram-negative bacteria. It is a prodrug form of garenoxacin, which is designed to enhance its solubility and bioavailability. The substance exhibits a unique mechanism of action by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication and transcription. Garenoxacin mesylate is typically administered orally and is known for its favorable pharmacokinetic properties, including good tissue penetration. It is primarily used in the treatment of respiratory tract infections and skin infections. The mesylate salt form enhances stability and solubility, making it more effective in clinical applications. As with many antibiotics, the potential for developing resistance is a concern, necessitating careful use and adherence to prescribed regimens. Safety and efficacy profiles are established through clinical trials, and like other medications, it may have side effects that require monitoring during treatment.

Formula: C₂₃H₂₀F₂N₂O₄·CH₄O₃S

InChI: InChI=1S/C23H20F2N2O4.CH4O3S/c1-11-15-5-2-12(8-13(15)9-26-11)16-6-7-17-19(21(16)31-23(24)25)27(14-3-4-14)10-18(20(17)28)22(29)30;1-5(2,3)4/h2,5-8,10-11,14,23,26H,3-4,9H2,1H3,(H,29,30);1H3,(H,2,3,4)/t11-;/m1./s1

InChI key: InChIKey=UPHLDCUEQOTSAD-RFVHGSKJSA-N

SMILES: O(C(F)F)C1=C2N(C=C(C(O)=O)C(=O)C2=CC=C1C=3C=C4C(=CC3)[C@@H](C)NC4)C5CC5.S(C)(=O)(=O)O

Synonyms:

• BMS 284756
• 3-Quinolinecarboxylic acid, 1-cyclopropyl-8-(difluoromethoxy)-7-[(1R)-2,3-dihydro-1-methyl-1H-isoindol-5-yl]-1,4-dihydro-4-oxo-, methanesulfonate (1:1)
• T 3811ME
• 3-Quinolinecarboxylic acid, 1-cyclopropyl-8-(difluoromethoxy)-7-[(1R)-2,3-dihydro-1-methyl-1H-isoindol-5-yl]-1,4-dihydro-4-oxo-, monomethanesulfonate
• Garenoxacin mesylate

Garenoxacin mesylate

CAS: 223652-82-2

Garenoxacin mesylate: potent oral antibiotic for respiratory pathogens, including resistant, Gram-negative, and Gram-positive bacteria.

Formula: C₂₄H₂₄F₂N₂O₇S

Color and Shape: Solid

Molecular weight: 522.52

Ref: TM-T7804L

Garenoxacin mesylate

CAS: 223652-82-2

Garenoxacin mesylate is a peptide that is used as a research tool for the study of ion channels. It has been shown to act as an inhibitor and activator of voltage-gated potassium channels, which are important in nerve transmission and muscle contraction. Garenoxacin mesylate also binds to antibody molecules and induces conformational changes in their structure. This binding prevents the antibody from binding with its receptor or ligand, preventing protein interactions and signaling pathways.

Formula: C₂₄H₂₄F₂N₂O₇S

Purity: Min. 95%

Molecular weight: 522.5 g/mol

Ref: 3D-YIA65282