CAS 22373-78-0: Monensin Sodium
Description:Monensin sodium is a polyether ionophore antibiotic primarily used as a feed additive in livestock to improve growth rates and feed efficiency. It is produced by the fermentation of the bacterium *Streptomyces cinnamonensis*. This compound exhibits a complex structure characterized by a cyclic polyether backbone, which allows it to transport monovalent cations, such as sodium and potassium, across biological membranes. Monensin sodium is known for its ability to disrupt ion gradients, leading to altered cellular metabolism in certain microorganisms, which is why it is effective against various protozoa and gram-positive bacteria. In veterinary medicine, it is utilized to prevent coccidiosis in poultry and to enhance weight gain in ruminants. However, its use must be carefully managed due to potential toxicity in non-target species and the development of resistance in pathogens. Additionally, monensin sodium has been studied for its potential applications in human medicine, particularly in cancer therapy, due to its ability to induce apoptosis in certain cancer cells.
Formula:C36H61NaO11
InChI:InChI=1S/C36H62O11.Na/c1-10-34(31-20(3)16-26(43-31)28-19(2)15-21(4)36(41,18-37)46-28)12-11-27(44-34)33(8)13-14-35(47-33)17-25(38)22(5)30(45-35)23(6)29(42-9)24(7)32(39)40;/h19-31,37-38,41H,10-18H2,1-9H3,(H,39,40);/t19-,20-,21+,22+,23-,24-,25-,26+,27+,28-,29+,30-,31+,33-,34-,35+,36-;/m0./s1
InChI key:InChIKey=JJYGTKRWVAEORV-FBZUZRIGSA-N
SMILES:[Na].O=C(O)C(C)C(OC)C(C)C1OC2(OC(C)(CC2)C3OC(CC)(CC3)C4OC(CC4C)C5OC(O)(CO)C(C)CC5C)CC(O)C1C
- Synonyms:
- 1,6-Dioxaspiro[4.5]decane-7-butyric acid, 2-[5-ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β-methoxy-α,γ,2,8-tetramethyl-, monosodium salt
- 1,6-Dioxaspiro[4.5]decane-7-butyricacid,2-[5-ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-.beta.-methoxy-.alpha.,.gamma.-2,8-tetramethyl-,monosodiumsal
- 1,6-Dioxaspiro[4.5]decane-7-butyricacid,2-[5-ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-.beta.-methoxy-.alpha.,.gamma.-2,8-tetramethyl-,monosodiumsalt
- CRC Rumensin
- Coban
- Coban 45
- Coban45
- Gamma,2,8-Tetramethyl--Furyl)-2-Furyl)-9-Hydroxy-Beta-Methoxy-Alphmonosod
- Kexxtone
- Methyl-5-(Tetrahydro-6-Hydroxy-6-(Hydroxymethyl)-3,5-Dimethyl-2H-Pyran-2-Yl)-2
- See more synonyms
- Monensin A sodium salt
- Monensin sodium salt
- Monensin, monosodium salt
- Monensin, sodium salt (1:1)
- Monensin,Monosodiumsalt
- Monensin,monosodiumsalt(9CI)
- Monesin Sodium
- NSC 343257
- Rumensin
- Sodium Monesin
- Sodium monensin
- sodium (2R,3S,4R)-4-[(2R,5R,7S,8R,9S)-2-{(2S,2'S,3'R,5R,5'S)-2-ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-2,2'-bifuran-5-yl}-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methylpentanoate
- sodium (3R,4S)-4-[(2S,5R,7S,8R,9S)-2-{(2S,2'R,3'S,5R,5'R)-2-ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-2,2'-bifuran-5-yl}-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methylpentanoate
