CAS 22373-78-0

Monensin Sodium

Description:

Monensin sodium is a polyether ionophore antibiotic primarily used as a feed additive in livestock to improve growth rates and feed efficiency. It is produced by the fermentation of the bacterium *Streptomyces cinnamonensis*. This compound exhibits a complex structure characterized by a cyclic polyether backbone, which allows it to transport monovalent cations, such as sodium and potassium, across biological membranes. Monensin sodium is known for its ability to disrupt ion gradients, leading to altered cellular metabolism in certain microorganisms, which is why it is effective against various protozoa and gram-positive bacteria. In veterinary medicine, it is utilized to prevent coccidiosis in poultry and to enhance weight gain in ruminants. However, its use must be carefully managed due to potential toxicity in non-target species and the development of resistance in pathogens. Additionally, monensin sodium has been studied for its potential applications in human medicine, particularly in cancer therapy, due to its ability to induce apoptosis in certain cancer cells.

Formula: C₃₆H₆₃NaO₁₂

InChI: InChI=1/C36H62O11.Na/c1-10-34(31-20(3)16-26(43-31)28-19(2)15-21(4)36(41,18-37)46-28)12-11-27(44-34)33(8)13-14-35(47-33)17-25(38)22(5)30(45-35)23(6)29(42-9)24(7)32(39)40;/h19-31,37-38,41H,10-18H2,1-9H3,(H,39,40);/q;+1/p-1/t19-,20+,21+,22+,23+,24+,25-,26-,27+,28-,29-,30-,31-,33+,34-,35+,36-;/m0./s1

InChI key: InChIKey=JJYGTKRWVAEORV-FBZUZRIGSA-N

SMILES: C[C@@]1(O[C@]2(O[C@]([C@H]([C@H]([C@@H](C(O)=O)C)OC)C)([C@H](C)[C@@H](O)C2)[H])CC1)[C@@]3(O[C@@](CC)(CC3)[C@@]4(O[C@](C[C@@H]4C)([C@]5(O[C@](CO)(O)[C@H](C)C[C@@H]5C)[H])[H])[H])[H].[Na]

Synonyms:

• 1,6-Dioxaspiro[4.5]decane-7-butyric acid, 2-[5-ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β-methoxy-α,γ,2,8-tetramethyl-, monosodium salt
• 1,6-Dioxaspiro[4.5]decane-7-butyricacid,2-[5-ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-.beta.-methoxy-.alpha.,.gamma.-2,8-tetramethyl-,monosodiumsal
• 1,6-Dioxaspiro[4.5]decane-7-butyricacid,2-[5-ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-.beta.-methoxy-.alpha.,.gamma.-2,8-tetramethyl-,monosodiumsalt
• CRC Rumensin
• Coban
• Coban 45
• Coban45
• Gamma,2,8-Tetramethyl--Furyl)-2-Furyl)-9-Hydroxy-Beta-Methoxy-Alphmonosod
• Kexxtone
• Methyl-5-(Tetrahydro-6-Hydroxy-6-(Hydroxymethyl)-3,5-Dimethyl-2H-Pyran-2-Yl)-2
• Monensin A sodium salt
• Monensin sodium salt
• Monensin, monosodium salt
• Monensin, sodium salt (1:1)
• Monensin,Monosodiumsalt
• Monensin,monosodiumsalt(9CI)
• Monesin Sodium
• NSC 343257
• Rumensin
• Sodium Monesin
• Sodium monensin
• sodium (2R,3S,4R)-4-[(2R,5R,7S,8R,9S)-2-{(2S,2'S,3'R,5R,5'S)-2-ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-2,2'-bifuran-5-yl}-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methylpentanoate
• sodium (3R,4S)-4-[(2S,5R,7S,8R,9S)-2-{(2S,2'R,3'S,5R,5'R)-2-ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-2,2'-bifuran-5-yl}-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methylpentanoate
• Monensin sodium
• MONENSINSODIUM,USP
• Monensin Sodium (200 mg)
• 1,6-Dioxaspiro[4.5] decane-7-butyric acid, 2-[5-ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-.beta.-methoxy-.alpha.,.gamma.-2,8-tetramethyl-, monosodium salt
• Monensin sodium salt,Monensin A sodium salt
• 2-[5-Ethyltetrahydro-5-[tetrahydro-3-Methyl-5-[tetrahydro-6-hydroxy-6-(hydroxyMethyl)-3,5-diMethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β-Methoxy-α,γ,2,8-tetraMethyl-
• 1,6-Dioxaspiro[4.5]decane-7-butyric acid, 2-[5-ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β-methoxy-α,γ,2,8-tetramethyl-, monosodium salt (8CI)
• Sodium 4-[2-[2-Ethyl-3'-methyl-5'-(tetrahydro-6-hydroxy-6-hydroxymethyl-3,5-dimethylpyran-2-yl)perhydro-2,2'-bifuran-5-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl}-3-methoxy-2-methylpentanoate
• Sodiummonensin
• 1,6-Dioxaspiro[4.5]decane-7-butyric acid, 2-[5-ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydrox y-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-.beta.-metho xy-.alpha.,.gamma.,2,8-tetramethyl-, monosodium salt (8CI
• 4-[2-[5-Ethyl-5-[5-[6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-oxan-2-yl]-3-methyl-oxolan-2-yl]oxolan-2-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methyl-pentanoic acid monosodium salt
• MONENSIN SODIUM SALT 97%
• MONENSIN SODIUM SALT HYDRATE
• Previouscas:22136-43-2
• Monensin sodiuM salt(Coban)
• MONENSIN SODIUM (Monensin A is shown)

Monensin Sodium Salt

CAS: 22373-78-0

Formula: C₃₆H₆₁NaO₁₁

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystaline

Molecular weight: 692.86

Ref: 3B-M2573

Monensin sodium salt, 90% min.

CAS: 22373-78-0

Monensin sodium salt is used in potentiometric and spectroscopic studies of alkali metal ion complexes. Monensin (Na) is a polyether small molecule ionophore, capable of forming stable complexes to monovalent cations with specific affinity for Na+. Monensin presents a highly lipophilic scaffold arou

Formula: C₃₆H₆₁NaO₁₁

Purity: 90%

Color and Shape: Powder, White to off-white

Molecular weight: 692.86

Ref: 02-J61669

Monensin Sodium

CAS: 22373-78-0

Antibiotics nesoi

Formula: C₃₆H₆₁NaO₁₁

Color and Shape: Tan Off-White Crystalline Powder

Molecular weight: 692.86 g/mol

Ref: 45-1445481

Monensin sodium salt

CAS: 22373-78-0

Monensin sodium is an antiprotozoal agent produced by Streptomyces cinnamonensis.Monensin sodium salt (Monensin A sodium salt) causes a marked enlargement of

Formula: C₃₆H₆₁NaO₁₁

Purity: 90% - 98.9%

Color and Shape: Almost White Solid

Molecular weight: 692.85

Ref: TM-T1033

Monensin sodium salt

CAS: 22373-78-0

Formula: C₃₆H₆₁NaO₁₁

Purity: ≥ 900μg/mg (dried basis)

Color and Shape: White to pale yellow powder

Molecular weight: 692.86

Ref: 7W-GA4916

Monensin sodium salt

CAS: 22373-78-0

Monensin sodium salt

Purity: ≥90%

Molecular weight: 692.85g/mol

Ref: 54-BUP16008

Monensin sodium 100 µg/mL in Acetonitrile

CAS: 22373-78-0

Formula: C₃₆H₆₁O₁₁·Na

Color and Shape: Single Solution

Molecular weight: 692.85

Ref: 04-A15291000AL-100

Monensin sodium

Controlled Product

CAS: 22373-78-0

Formula: C₃₆H₆₁O₁₁·Na

Color and Shape: Neat

Molecular weight: 692.85

Ref: 04-C15291000

Monensin sodium

CAS: 22373-78-0

Formula: C₃₆H₆₂O₁₁

Purity: 99%

Color and Shape: White Powder

Molecular weight: 670.881

Ref: BP-BP2018

Monensin Sodium Salt

CAS: 22373-78-0

Formula: C₃₆H₆₁O₁₁·Na

Molecular weight: 669.87 22.99

Ref: 4Z-M-189001

Monensin Sodium Salt

Controlled Product

CAS: 22373-78-0

Stability Hygroscopic
Applications Polyether antibiotic. Coccidiostat.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Day, et al.: Antimicrob. Agents Chemother., 4, 410 (1973), Buchko, S., et al.: J. Food Prot., 63, 1467 (2000), De Leener, E., et al.: Microb. Drug Resist., 10, 341 (2004), Sanderson, M., et al.: Vet. Microbiol., 110, 125 ( 2005),

Formula: C₃₆H₆₁O₁₁·Na

Color and Shape: Beige

Molecular weight: 692.85

Ref: TR-M515600

Monensin sodium

CAS: 22373-78-0

Monensin sodium is a polyether antibiotic with action on ion transport across bacterial cell membranes and is used for preventing coccidiosis and improving feed efficiency in livestock.

Formula: C₃₆H₆₁NaO₁₁

Purity: (%) Min. 90%

Color and Shape: White Off-White Powder

Molecular weight: 692.85 g/mol

Ref: 3D-AM26044

Monensin Sodium Salt (MSN), 97%

CAS: 22373-78-0

Formula: C₃₆H₆₁NaO₁₁

Purity: min. 97%

Color and Shape: White to off-white, Powder

Molecular weight: 692.85

Ref: SR-55690